Results 101 to 110 of about 14,268,580 (205)

L-Asparaginase - Perspectives On The Mechanisms Of Action And Resistance

, 1997
L-Asparaginase, the enzyme that hydrolyzes asparagine to yield aspartic acid and ammonia, is isolated from various bacterial sources and is an effective and well-accepted chemotherapeutic agent, especially in the treatment of pediatric acute ...

core  

Catalytic activity of L-asparaginase C77-105S mutant.

, 2018
Catalytic activity of L-asparaginase C77-105S mutant.
Josell Ramirez-Paz (3852553), Virginia A. Rojas-Nieves (5565800), Zhongfang Chen (1288152), Kai Griebenow (23303), Manoj Saxena (2624236), Louis J. Delinois (5565791), Shiru Lin (5565797), Freisa M. Joaquín-Ovalle (5565794)   +7 more
core   +1 more source

Production optimization and characterization of anticancer enzyme L-Asparaginase from Bacillus Sp. using Moringa Oleifera Seeds [PDF]

, 2018
L-Asparaginase (L-asparagine amino hydrolase 3.5.1.1) constitutes one of the most biotechnologically and bio medically important group of therapeutic enzymes accounting for about 40% of the total worldwide enzyme sales [1, 2].
Makky, Essam A., M. M., Yusoff, M., Khan, Batool, T.   +3 more
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Catalytic activity of cysteine-directed crosslinked L-asparaginase.

, 2018
Catalytic activity of cysteine-directed crosslinked L-asparaginase.
Josell Ramirez-Paz (3852553), Virginia A. Rojas-Nieves (5565800), Zhongfang Chen (1288152), Kai Griebenow (23303), Manoj Saxena (2624236), Louis J. Delinois (5565791), Shiru Lin (5565797), Freisa M. Joaquín-Ovalle (5565794)   +7 more
core   +1 more source

GLUTAMINASE AND UREASE-FREE ANTITUMOR EFFECTIVE L-ASPARAGINASE-PRODUCING MICROORGANISMS ISOLATION

, 2021
L-asparaginase (EC 3.5.1.1) is a biopharmaceutical enzyme that catalyzes the hydrolysis of Lasparagineto L-aspartic acid and ammonia. Currently, L-asparaginase is used clinically, for thechemotherapeutic treatment of childhood acute lymphoblastic ...
Gülmez, Özlem, Gökçe, Emine, Özdal, Murat   +2 more
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Cloning, expression and characterization of L-Asparaginase from Mesoflavibacter zeaxanthinifaciens S86

, 2013
L-Asparaginase(EC 3.5.1.1) catalyzes the hydrolysis of L-asparagine to L-aspartic acid and ammonia. L-asparaginase has been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia.
오철홍, 김지형, 이수진, 이영득, 전선미, 강도형, 권영경, 허수진   +7 more
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Acute Pancreatitis Complicating L-asparaginase Therapy in Pediatric Oncology: A Case Report. [PDF]

Cureus
Larda L, Ryouni K, Kawtar E, Mounia EA, Benajiba N.   +4 more
europepmc   +1 more source

L-ASPARAGINASE PHARMACOKINETICS AND ASPARAGINE LEVELS IN CEREBROSPINAL-FLUID OF RHESUS-MONKEYS AND HUMANS

, 1981
L-Asparaginase has been widely used for the treatment of acute lymphoblastic leukemia. Therapeutic and toxic effects in the central nervous system have been noted with systemic treatment.
Riccardi, Riccardo
core  

L-asparaginase by filamentous fungi and yeasts from lichens and soils across maritime Antarctic islands. [PDF]

Extremophiles
da Silva AV, Ferro BEF, Medeiros VDV, Dos Santos VC, da Silva MNP, Dos Santos Duarte CK, de Queiroz AC, Moreira MSA, Rosa LH, Duarte AWF.   +9 more
europepmc   +1 more source

Unveiling a putative class 3 L-asparaginase in Glutamicibacter sp.: from soil isolation to in silico characterization. [PDF]

BMC Biotechnol
Mofidi M, Ebrahimipour G, Irani MA, Etemadi A, Yaghoubi-Avini M.   +4 more
europepmc   +1 more source