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Monoclonal antibodies to L-asparaginase
Experientia, 1984Five hybridomas secreting monoclonal antibody to E. coli L-asparaginase were isolated. These monoclonal antibodies were classified into 3 different subclasses; Ig G1 (1 clone), Ig G2 (2 clones) and Ig G3 (2 clones). One of them possessed anti-L-asparaginase neutralizing activity.
Kitao, T, Hattori, K
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Experimental Immunosuppression with L-Asparaginase
1970During the last year several papers were published dealing with an immunosuppressive action of Escherichia coli L-asparaginase. Hobik described the inhibition of the graft-versus-host reaction in rats and mice. Bertelli, Donati and Trabucchi, using very high doses of L-asparaginase, found a prolongation of the rejection time of allogeneic and ...
K, Lauenstein +3 more
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1971
Publisher Summary This chapter discusses the occurrence and physiological properties of L -Asparaginase. It also discusses the isolation procedure for guinea pig serum asparaginase and Escherichia coli asparaginase. L -Asparaginase that catalyzes the hydrolysis of L-asparagine to L-aspartic acid and ammonia is widely distributed.
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Publisher Summary This chapter discusses the occurrence and physiological properties of L -Asparaginase. It also discusses the isolation procedure for guinea pig serum asparaginase and Escherichia coli asparaginase. L -Asparaginase that catalyzes the hydrolysis of L-asparagine to L-aspartic acid and ammonia is widely distributed.
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L-ASPARAGINASE AND BLASTOGENESIS
The Lancet, 1970D, Benezra, A, Hochman, R, Pitaro
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