We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Clinical impacts of the concomitant use of L-asparaginase and total parenteral nutrition containing L-aspartic acid in patients with acute lymphoblastic leukemia. [PDF]
Ko M +6 more
europepmc +1 more source
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source
Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]
Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
core +2 more sources
Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei +7 more
wiley +1 more source
Rambutan seed waste-derived nitrogen-doped carbon dots with l-aspartic acid for the sensing of Congo red dye. [PDF]
Zulfajri M +3 more
europepmc +1 more source
Stereoselective Synthesis of Optically Active Aspartic Acid from Derivatives of Fumaric Acid and Maleic Acid [PDF]
Stereoselective synthesis of optically active aspartic acid from derivatives of fumaric acid and maleic ...
Harada, K., Matsumoto, K.
core +1 more source
OsGSK2‐OsTCP19 module regulating nitrate response and lateral root (LR) development. Low‐nitrate condition results in reduced BR response, accumulation of OsGSK2 and phosphorylated OsTCP19, which suppresses the expression of nitrate‐responsive genes and LR‐development genes and impairs rice growth.
Yongqiang Liu +11 more
wiley +1 more source
The effects of aspartic acid on the seed germination, seedling growth (radicle lenght, radicle number and fresh weight), mitotic index and chromosome aberrations of Allium cepa L. germinated under saline conditions were examined in this study.
Kürşat Çavuşoğlu +2 more
doaj
Investigation of Operation Strategy Based on Solution pH for Improving the Crystal Quality Formed during Reactive Crystallization of l-Aspartic Acid. [PDF]
Amari S, Sugawara C, Kudo S, Takiyama H.
europepmc +1 more source

