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Synthesis of Deuterium Derivatives of L-Aspartic Acid

The Journal of Biochemistry, 1962
All the possibie deuterium derivatives of L-aspartic acid were prepared by combining various enzymic and chemical reactions. Deuterium analysis by mass spectrometry showed the syntheses proceeded as expected. A comparison of the infrared absorption spectra of the 16 preparations showed they were all different and not contaminated with each other ...
N, TAMIYA, T, OSHIMA
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L-ASPARTIC ACID FORMATION PROM N-ACETYL-L-ASPARTIC ACID IN THE BRAIN

Psychiatry and Clinical Neurosciences, 1961
Summary 1. Radioactive L-aspartic acid was produced by incubating C i*-N-acetyl-L-aspartic acid with a mouse brain homogenate. 2. Glutathione and Co++ must co-exist to activate this reaction. However, the reaction could be performed more or less by using Fe++, Cu++, Ca++, and Zn*+ instead of Co*H. 3.
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Bioproduction of l-Aspartic Acid and Cinnamic Acid by l-Aspartate Ammonia Lyase from Pseudomonas aeruginosa PAO1

Applied Biochemistry and Biotechnology, 2016
Aspartase (L-aspartate ammonia lyase, EC 4.3.1.1) catalyses the reversible amination and deamination of L-aspartic acid to fumaric acid which can be used to produce important biochemical. In this study, we have explored the characteristics of aspartase from Pseudomonas aeruginosa PAO1 (PA-AspA).
Arti T, Patel   +4 more
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L-Aspartic Acid

2001
(l) [56-84-8] C4H7NO4 (MW 133.10) (d) [1783-96-6] (dl) [617-45-8] InChI = 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1 InChIKey = CKLJMWTZIZZHCS-UWTATZPHSA-N InChI = 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1 InChIKey = CKLJMWTZIZZHCS-UWTATZPHSA-N InChI = 1S/C4H7NO4/c5-2(4(
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The Acidulant Properties of L‐aspartic Acid

Journal of Food Science, 1965
SUMMARY Preliminary studies suggest L‐aspartic acid possesses acidulant properties of potential use in foods. Present costs are not competitive with citric acid, though special application may exist. The concept of using amino acids as flavoring materials is suggested, with a second role in improving nutritional quality.
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Mutagenicity studies with N-acetyl-l-aspartic acid

Food and Chemical Toxicology, 2009
Analytical studies have reported that N-acetyl-L-aspartic acid (NAA) is present at low concentrations in many foods. The current studies were conducted to assess the mutagenicity of NAA using standard OECD guideline in vitro bacterial and in vivo mammalian mutagenicity studies.
Sule, Karaman   +4 more
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Active transport of l-aspartic acid in Neurospora crassa

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1971
Abstract Transport of l -aspartic acid in Neurospora crassa conidia is shown to be mediated by neutral and general amino acid transport systems. The transport activity is dependent on pH and results in accumulation of l -aspartic acid against a gradient. Mutants deficient in transport of l -aspartic acid are described.
L, Wolfinbarger   +2 more
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Thermodynamics of the conversion of aqueous l-aspartic acid to fumaric acid and ammonia

Biophysical Chemistry, 1986
The thermodynamics of the conversion of aqueous L-aspartic acid to fumaric acid and ammonia have been investigated using both heat conduction microcalorimetry and high-pressure liquid chromatography. The reaction was carried out in aqueous phosphate buffer over the pH range 7.25-7.43, the temperature range 13-43 degrees C, and at ionic strengths ...
R N, Goldberg   +3 more
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Synthesis of decapeptide ofl-aspartic acid and benzyl-l-aspartic acid by solid phase peptide synthesis

Archives of Pharmacal Research, 2005
Polyene macrolide amphotericin B (AmB) is the drug of choice for the treatment of disseminated fungal infections. However, because of its pronounced side effects, the drug has limited applicability. There are few interesting reports, which state that co-administration of the drug with homo-peptide of polyaspartic acid reduces the side effects of the ...
Bong K, Yoo   +3 more
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