Results 191 to 200 of about 56,359 (264)

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Extending dynamic and operational range of the biosensor responding to l-carnitine by directed evolution. [PDF]

Synth Syst Biotechnol
Li T, Dong H, Li J, Wang H, Pu C, Chen S, Yang Z, Ren X, Liu X, Jin Z, Zhang D.   +10 more
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, Volume 13, Issue 45, 13 August 2026.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, Volume 13, Issue 45, 13 August 2026.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Punicalagin is the key pomegranate polyphenol inhibiting gut microbial trimethylamine (TMA) production from L-carnitine in an <i>in vitro</i> human colon model.

Food Funct
Haarhuis JE, Gamal El-Din MI, Lamprinaki D, Kroon PA.   +3 more
europepmc   +1 more source

Eco-Friendly Synthesis of L-Carnitine-Loaded β-Cyclodextrin-Functionalized N-Doped Carbon Dots Using <i>Rhododendron</i> Species: Antioxidant and Antimicrobial Activities and In Vivo Acute Toxic Effects on Nauplii. [PDF]

Nanomaterials (Basel)
Özkan Y, Akyol A.
europepmc   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, Volume 101, Issue 8, Page 1980-1996, August 2026.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Rumen microbiota-host interactions regulate intramuscular fat deposition in cattle via the alpha-linolenic acid-fatty acid β-oxidation/L-carnitine-MPO axis. [PDF]

Microbiome
Zhang WT, Wang ML, Liu CY, Li C, He XP, Wang HB, Zan LS, Cheng G.   +7 more
europepmc   +1 more source

Diagnosis of deep vein thrombosis from γ-butylbetaine and L-carnitine in plasma and urine based on untargeted and targeted metabolomics. [PDF]

Sci Rep
Zeng W, Wang Q, Li X, Wang Z, Chi J, Yang Z, Li J, Gao YY, Qu M.   +8 more
europepmc   +1 more source

Unlocking Relief: Investigating the Impact of a Fixed Combination of Acetyl-L-Carnitine and Palmitoylethanolamide on Traumatic Acute Low Back Pain. [PDF]

Eur J Neurol
Cominacini M, Valenti MT, Braggio M, Caramori A, Vedovi E, Dalle Carbonare L.   +5 more
europepmc   +1 more source