Results 211 to 220 of about 56,359 (264)
Some of the next articles are maybe not open access.
Therapeutic Effects of l‐Carnitine and Propionyl‐l‐carnitine on Cardiovascular Diseases: A Review
Annals of the New York Academy of Sciences, 2004Abstract: Several experimental studies have shown that levocarnitine reduces myocardial injury after ischemia and reperfusion by counteracting the toxic effect of high levels of free fatty acids, which occur in ischemia, and by improving carbohydrate metabolism.
FERRARI, Roberto +5 more
openaire +3 more sources
l -Carnitine and heart disease
Life Sciences, 2018Cardiovascular disease (CVD) is a key cause of deaths worldwide, comprising 15-17% of healthcare expenditure in developed countries. Current records estimate an annual global average of 30 million cardiac dysfunction cases, with a predicted escalation by two-three folds for the next 20-30years. Although β-blockers and angiotensin-converting-enzymes are
Zhong-Yu Wang +4 more
openaire +2 more sources
l-carnitine treatment of anemia
American Journal of Kidney Diseases, 2003Recombinant human erythropoietin (rHuEPO) and iron supplementation have had a profoundly positive impact on the anemia of patients with chronic kidney disease. However, a significant number of patients remain hyporesponsive to rHuEPO, with hemoglobin values less than target levels.
Thomas A, Golper +3 more
openaire +2 more sources
Excretion of l-carnitine in man
Clinica Chimica Acta, 1971Abstract 1. 1. The method for carnitine determination described by Marquis and Fritz has been adapted for determination of carnitine in human urine. 2. 2. The excretion of carnitine in normal men was 175 ± 80.7 μ moles per day (mean ± S.D.) and in women 86 ± 72.6 μ moles per day.
G, Cederblad, S, Lindstedt
openaire +2 more sources
Butyrobetaine is equal to l-carnitine in elevating l-carnitine levels in rats
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991This work shows that butyrobetaine administered to rats in a single dose can be highly effective in elevating L-carnitine levels in all tissues. This ability of butyrobetaine was compared to that of L-carnitine. In an experiment with tracer dose of the compounds, 12 h following administration of [3H]butyrobetaine plasma and tissues contained ...
openaire +2 more sources
Studies on the Kinetics and Application of L-Carnitine Amidase for the Production of L-Carnitine
Biocatalysis and Biotransformation, 1995The kinetics of L-carnitine amidase from the newly isolated microorganism DSM 6320 is complex; the enzyme is competitively inhibited by the product L-carnitine as well as the unreactive enantiomer of the substrate, D-carnitine amide. The second reaction product, ammonia, does not affect the rate of hydrolysis.
U. Joeres +3 more
openaire +1 more source
L-Carnitine and Peritoneal Dialysis
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2000Asearch of PubMed (1) resulted in 6499 citations having the term “carnitine” in the title or key words. Of these citations, 120 pertained to carnitine in relation to dialysis. Despite this extensive literature on the medical uses of carnitine (Table 1), the specific medical uses for this compound remain unclear, particularly its utility in dialysis ...
openaire +2 more sources
L‐Carnitine in Dialysis Patients
Seminars in Dialysis, 2001ABSTRACTHemodialysis (HD) patients often have low serum concentrations of free L‐carnitine and decreased skeletal muscle stores. As L‐carnitine is an essential cofactor in fatty acid and energy metabolism, it is possible that abnormal carnitine metabolism in dialysis patients may be associated with clinical problems such as skeletal myopathies ...
openaire +2 more sources
[L-carnitine in peritoneal dialysis].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2011L-carnitine is an important compound involved both in the transfer of activated long-chain fatty acids across the mitochondrial membrane and in the modulation of the acyl coenzyme A/free coenzyme A ratio in various intracellular compartments. These processes activate several metabolic and cellular functions, and L-carnitine supplementation proved able ...
De Vecchi Amedeo +3 more
openaire +2 more sources
The Medical letter on drugs and therapeutics, 2004
Although advertised on the Internet for weight loss, prevention of aging and enhancement of athletic and sexual performance, levocarnitine has only one well-established indication, and that is for treatment of carnitine deficiency. In clinical trials, the drug also seems to have had modest effects in some other conditions, particularly intermittent ...
openaire +1 more source
Although advertised on the Internet for weight loss, prevention of aging and enhancement of athletic and sexual performance, levocarnitine has only one well-established indication, and that is for treatment of carnitine deficiency. In clinical trials, the drug also seems to have had modest effects in some other conditions, particularly intermittent ...
openaire +1 more source