Results 191 to 200 of about 11,284,409 (311)

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Remodeling of Perineuronal Nets in the Striato-Cortical Axis in L-DOPA-Induced Dyskinesia Rat Model. [PDF]

Int J Mol Sci
Bilbay NT, Tel BC, Akkus G, Cakir-Aktas C, Solakoglu T, Yalcin-Cakmakli G, Elibol B.   +6 more
europepmc   +1 more source

The BioSAXS laboratory of the ITACA.SB Research Infrastructure

Journal of Applied Crystallography, EarlyView.
We present a versatile state‐of‐the‐art X‐ray scattering laboratory within the ITACA.SB Research Infrastructure, enabling multi‐scale structural characterization of complex biological specimens and advanced materials through integrated small‐ and wide‐angle X‐ray scattering (SAXS/WAXS) techniques.
Francesco Scattarella, Davide Altamura, Vincenzo Mangini, Teresa Sibillano, Erika Manicone, Rocco Lassandro, Liberato De Caro, Gemma Newby, Cinzia Giannini   +8 more
wiley   +1 more source

Agaricus arvensis extract-coated functionalized silver nanoparticles for effective aerobic biotransformation of synthetic L-tyrosine to L-DOPA. [PDF]

AMB Express
Li Y, Ali S, Khan QF, Ahmad MU, Fatima L, Shah TA, Assefa M, Al-Emam A.   +7 more
europepmc   +1 more source

Goose herbivory alters soil microbial community functional potential in a sub‐Arctic wetland

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Herbivory alters below‐ground resource dynamics via direct and indirect mechanisms, yet its effects on microbial functional potential remain poorly understood. This limits our understanding of the mechanisms that link animal, plant and microbial functional roles in ...
Jaron Adkins, Bonnie G. Waring, Karen H. Beard, Ryan T. Choi, Taylor Saunders, Emily A. Chavez, Lindsay R. Miller, Edd Hammill, Trisha B. Atwood   +8 more
wiley   +1 more source

L-DOPA mõju sensoorsele funktsioonile in vivo

Levodopa (L-DOPA) is a compound that is used as a key medication in treating Parkinson’s disease (PD), particularly in managing bradykinetic symptoms of the disorder.
Rusetskaya, Anna
core  

Males are worse mothers: Comparing care patterns in a facultatively caring beetle

Insect Science, EarlyView.
Why should biparental care exist if offspring fare just as well when only one parent is present? In the facultatively dependent burying beetle, Nicrophorus vespilloides, manipulating environmental quality reveals that biparental care benefits offspring in form of lower personal immune requirement and parents in term of weight gain.
Leon Müller, Patrick Limburg, Maximilian Körner   +2 more
wiley   +1 more source

Effects of Dopaminergic Therapy with Levodopa (L-DOPA) on Fear and Anxiety-Related Circuits and Symptoms in Patients with Depression and Higher Inflammation. [PDF]

Brain Behav Immun
Craig GE, Mehta ND, Bekhbat M, Revill KP, Lucido MJ, Hong C, Wommack EC, Baer WM, Haroon E, Miller AH, Li Z, Felger JC.   +11 more
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Efficient synthesis of l-DOPA in <i>Escherichia coli</i> via cofactor and enzyme engineering. [PDF]

Synth Syst Biotechnol
Deng L, Ping J, Liu Z, Linghu K, Zhang H, Shan X, Zeng W, Li J, Zhou J.   +8 more
europepmc   +1 more source