Results 201 to 210 of about 11,284,409 (311)

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Preclinical Evaluation of Synthetic Biology-Driven Engineered <i>Escherichia coli</i> Nissle 1917 as a Living Therapeutic for Sustained L-DOPA Delivery. [PDF]

ACS Synth Biol
Abdalla A, Padhi P, Bakes N, Thyer R, Zenitsky G, Jin H, Anantharam V, Kanthasamy A, Ellington AD, Phillips GJ, Kanthasamy AG.   +10 more
europepmc   +1 more source

Microbiome‐mediated immunity: Limited support from the gazelle dung beetle

Ecological Entomology, EarlyView.
Digitonthophagus gazella rely on a maternally inherited microbiome passed across generations via a maternal faecal pellet called the pedestal. We experimentally manipulated the presence of the pedestal, providing it to some individuals while withholding it from others to determine how pedestal microbiota may affect beetle immune potential.
Joshua A. Jones, Irene L. G. Newton, Armin P. Moczek   +2 more
wiley   +1 more source

Regulating astrocytic activity in the dorsal striatum mitigates L-dopa-induced dyskinesia in Parkinson's disease. [PDF]

Sci Rep
Ryu YK, Park HY, Kim JE, Seo HH, Lee CH, Kim KS.   +5 more
europepmc   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

The FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal, Samara de Oliveira Pimentel, Bruno da Costa Rodrigues, Mauro Sérgio Gonçalves Pavão, Rodrigo Nunes da Fonseca, Cintia Monteiro de Barros   +5 more
wiley   +1 more source

Reduced Cortical Pyramidal Neuron Membrane Excitability and Synaptic Function in Parkinsonian Mice and Their Restoration by L-Dopa Treatment: Indirect Mediation by Striatal Dopaminergic Activity. [PDF]

Brain Sci
Chen H, Zhong M, Lin G, Liao FF, Zhou FM.   +4 more
europepmc   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

International Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster, T. Rogers, C. Vendruscolo, D. Roggenkamp, W. G. Philipp‐Dormston, F. Al‐Niaimi, S. Roussel, N. Kiss, H. Malik, D. Grozeva, K. S. Berger, C. Rauscher, L. Kolbe   +12 more
wiley   +1 more source

Probing the Mechanism of l‑DOPA 2,3-Dioxygenase Using Synthetic Derivatives of 3,4-Dihydroxyhydrocinnamic Acid. [PDF]

ACS Omega
Demisew AT, Cohen JR, Gruss EG, Bui JD, Steiner JL, Xhafkollari G, Marasco RN, Betonio M, Strzeminski D, Leyes Porello S, Colabroy KL, Peterson LW.   +11 more
europepmc   +1 more source

Analyses and Comparisons of the Antimicrobial-Cytotoxic Effects and Molecular Docking Study of L-DOPA and L-DOPA Methyl Ester

Yüksek biyouyumluluk, düşük sitotoksisite ve gelişmiş antibakteriyel özelliklere sahip bileşiklerin sentezlenmesinin artanönemi güncel araştırmalarda açıkça görülmektedir.
Balcı, Hüseyin, Aysan, Arzu, Karaca, Tuğçe Deniz, Sert, Yusuf   +3 more
core  

Dietary L‐Tyrosine Sustains Egg Production and Quality by Modulating Promoter CpG Methylation, Gene Expression, and Hormone Profiles in Reproductive Signalling Pathways of Aged Laying Hens

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Managing prolactin (PRL)‐mediated reproductive suppression is critical for maintaining egg production in commercial laying hens. L‐tyrosine (TYR), a precursor of dopamine (DA), may counteract age‐related reproductive decline by suppressing PRL, thereby sustaining productivity and egg quality in late‐phase laying hens.
Hasan Hüseyin İpçak
wiley   +1 more source