A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster +12 more
wiley +1 more source
Effects of Dopaminergic Therapy with Levodopa (L-DOPA) on Fear and Anxiety-Related Circuits and Symptoms in Patients with Depression and Higher Inflammation. [PDF]
Craig GE +11 more
europepmc +1 more source
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Preclinical Evaluation of Synthetic Biology-Driven Engineered <i>Escherichia coli</i> Nissle 1917 as a Living Therapeutic for Sustained L-DOPA Delivery. [PDF]
Abdalla A +10 more
europepmc +1 more source
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti +2 more
wiley +1 more source
Regulating astrocytic activity in the dorsal striatum mitigates L-dopa-induced dyskinesia in Parkinson's disease. [PDF]
Ryu YK +5 more
europepmc +1 more source
ABSTRACT Sleep bruxism (SB) is a motor activity characterized by repetitive masticatory muscle contractions during sleep, commonly associated with tooth damage and jaw pain or headache. Pharmacological management strategies targeting its central nervous system‐related mechanisms remain limited.
Matheus Herreira‐Ferreira +6 more
wiley +1 more source
Probing the Mechanism of l‑DOPA 2,3-Dioxygenase Using Synthetic Derivatives of 3,4-Dihydroxyhydrocinnamic Acid. [PDF]
Demisew AT +11 more
europepmc +1 more source
Reduced Cortical Pyramidal Neuron Membrane Excitability and Synaptic Function in Parkinsonian Mice and Their Restoration by L-Dopa Treatment: Indirect Mediation by Striatal Dopaminergic Activity. [PDF]
Chen H +4 more
europepmc +1 more source
Brain-region-specific lipid dysregulation in L-DOPA-induced dyskinesia in a primate model of Parkinson's disease. [PDF]
Kaya I +7 more
europepmc +1 more source

