Results 81 to 90 of about 20,262 (210)
Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng +5 more
wiley +1 more source
L-Homoserine Accumulation by a Threonine-Auxotroph of Escherichia coli
(1) E. coli (Thr-)が蓄積するアミノ酸を結晶として分離し,ペーパークロマトグラフィー,元素分析,赤外吸収スペクトル, E. coli 177-184によるbioassayによりL-ホモセリンと同定した. (2)L-ホモセリン蓄積のための培養条件を検討した結果,グリセロール5%,硫安1.4%, KH2PO4 0.1%, MgSO4. 7H2O 0.03%, L-スレオニン300γ/ml, CaCO3 2.0%の培地を用い,培養24時間にα-AB 3mg/mlを添加した場合にL-ホモセリン4.3mg/mlの蓄積量を得た.リジンの副生はほとんど認められなかった.L-ホモセリン蓄積はアミノ酸ではL-イソロイシン, α-ABで促進され, L-メチオニンで阻害された.有機酸ではクエン酸ソーダ ...
Haruo TANAKA, Kiyoshi NAKAYAMA
openaire +2 more sources
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson +8 more
wiley +1 more source
Marwa M Raafat,1 Marwa Ali-Tammam,1 Amal E Ali11Department of Microbiology & Immunology, Faculty of Pharmaceutical Sciences & Pharmaceutical Industries, Future University in Egypt (FUE), New Cairo, EgyptBackground: Quorum quenching, the ...
Raafat MM, Ali-Tammam M, Ali AE
doaj
The fitness of pseudomonas aeruginosa quorum sensing signal cheats is influenced by the diffusivity of the environment [PDF]
Experiments examining the social dynamics of bacterial quorum sensing (QS) have focused on mutants which do not respond to signals and the role of QS-regulated exoproducts as public goods.
Diggle, Stephen P. +3 more
core +2 more sources
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Pseudomonas chlororaphis PCL1391 controls tomato foot and root rot caused by Fusarium oxysporum f. sp. radicislycopersici. The production of phenazine-1-carboxamide (PCN) is crucial for this biocontrol activity.
Thomas F. C. Chin-A-Woeng +7 more
doaj +1 more source
Quorum Sensing in the Context of Food Microbiology [PDF]
Food spoilage may be defined as a process that renders a product undesirable or unacceptable for consumption and is the outcome of the biochemical activity of a microbial community that eventually dominates according to the prevailing ecological ...
Nychas, George-John E. +1 more
core +2 more sources
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani +2 more
wiley +1 more source
This study aimed to identify N-acylhomoserine lactone (AHL) produced by Hafnia alvei H4, which was isolated from spoiled instant sea cucumber, and to investigate the effect of AHLs on biofilm formation.
Hong-Man Hou +6 more
doaj +1 more source

