Results 241 to 250 of about 414,201 (353)

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

Advanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu, Zhennan Zhao, Hongsheng Wu, Sihuang Lin, Lin Huang, Guanjie Chen, Yi Yang, Hong Wang, Huijie Yan, Yonghui Shi, Liuyu Zhu, Guosheng Hu, Liling Zheng, Songying Ouyang   +13 more
wiley   +1 more source

ASH2L‐K312‐Lac Stimulates Angiogenesis in Tumors to Expedite the Malignant Progression of Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, ASH2L‐K312‐lac is identified as a critical driver that promotes the malignant progression of hepatocellular carcinoma (HCC). Furthermore, through a comprehensive series of cell biological and molecular biological experiments, integrated with diverse animal models and systematic application of high‐throughput sequencing technologies, it ...
Hexu Han, Shuai Wang, Lixing Ma, Haimeng Yin, Xinxiang Cheng, YiFan Wang, Suqin Xia, Yi Zhang, Yue Zhang, Rong Zhu, Cuixia Liu, Dakun Zhao, Xiangqian Gu, He Zhu, Yin Yuan   +14 more
wiley   +1 more source

Human D-Lactate Dehydrogenase Deficiency: A Case Report in a Young Boy. [PDF]

JIMD Rep
Sloth TB, Ørngreen MC, Ek J, Bache I, Wibrand F, Lund AM.   +5 more
europepmc   +1 more source

Are PM6:Y6 Bulk Heterojunction Photoactive Films Cytocompatible and Electrically Stable in Biological Environments?

Advanced Electronic Materials, EarlyView.
PM6:Y6 organic photovoltaic films are systematically studied to understand their potential for use in bioelectronics. The films exhibit excellent stability in simulated physiological environments, enabling consistent power delivery and demonstrating compatibility with rat neurons and the choriallantoic membrane of chicken embryos.
Mathias Polz, Konrad Binter, Kaila M. Yallum, Thomas Rath, Marta Nowakowska‐Desplantes, Christa Schimpel, Gerhard Sommer, Nassim Ghaffari‐Tabrizi‐Wizsy, Natalie Banerji, Gregor Trimmel, Theresa Rienmüller   +10 more
wiley   +1 more source

Characterization and Reuse of Lithium‐ion Battery Cathode Material Recovered Through a Bacterial Process

Advanced Energy Materials, EarlyView.
A sustainable bacteria‐based lithium‐ion battery cathode recycling method is optimized using engineering biology. The resulting biomineralized manganese carbonate species is found to be easily converted into an electrode material, via simple calcination.
Virginia Echavarri‐Bravo, Isolde Marsland, Mai‐Britt V. Jensen, Caroline Kirk, Louise E. Horsfall   +4 more
wiley   +1 more source

Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting. [PDF]

J Biomed Sci
Pan BS, Hsu CC, Wu HE, Chen YR, Zhou X, Wang SC, Li CY, Lin HK.   +7 more
europepmc   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Metabolic Engineering of <i>Escherichia coli</i> for Overproduction of Alpha-Ketoglutarate Using Crude Glycerol. [PDF]

J Agric Food Chem
Chiang CJ, Lin JH, Ta DT, Luu NL, Sun YC, Chao YP.   +5 more
europepmc   +1 more source

Cloning, nucleotide sequence, expression, and chromosomal location of ldh, the gene encoding L-(+)-lactate dehydrogenase, from Lactococcus lactis

Journal of Bacteriology, 1992
R. Llanos, A. Hillier, Russell Grimwade, L. R. Finch   +3 more
semanticscholar   +1 more source

Monolithic Biohybrid Flexure Mechanism Actuated by Bioengineered Skeletal Muscle Tissue

Advanced Intelligent Systems, EarlyView.
A scalable, monolithic biohybrid flexure mechanism is presented, integrating engineered skeletal muscle tissue with a soft, biocompatible, hollow silicone cylinder featuring dual pillars. Muscle contraction induces bending motion upon electrical stimulation, with performance governed by the structure's flexural rigidity.
Andrea Bartolucci, Judith Fuentes, Daniele Guarnera, Florencia Lezcano, Maria Crespo‐Cuadrado, Lorena Guachi‐Guachi, Francesco Iacoponi, Carlotta Salvatori, Riccardo Collu, Massimo Barbaro, Stefano Lai, Leonardo Ricotti, Samuel Sánchez, Lorenzo Vannozzi   +13 more
wiley   +1 more source