Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Optimization and scale up of L-malic acid production from methanol by the methylotrophic yeast Ogataea polymorpha. [PDF]
Mauri A +5 more
europepmc +1 more source
Chemically Fueled Systems Chemistry Across Length Scales
Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/functions like spatio‐temporal catalysis, oscillations, optical properties, and perform work.
Brigitte A. K. Kriebisch, Job Boekhoven
wiley +1 more source
Redox engineering of thermophilic fungus <i>Myceliophthora thermophila</i> enhances production of L‑malic acid by consolidated bioprocessing. [PDF]
Zhang Y +8 more
europepmc +1 more source
This work introduces an ultrafast thermal shock strategy to synthesize a CuNiSnLa medium‐entropy metallic glass (MEMG). The rapid heating and cooling process generates a robust, highly active catalyst for electrocatalytic nitrate reduction to ammonia (NRA).
Hongbo Chen +7 more
wiley +1 more source
Topoisomerase II-Like variants enhance acid tolerance and low-pH l-malic acid biosynthesis in metabolic engineered <i>Aspergillus nidulans</i>. [PDF]
Pei L, Dong Y, Chen Z, Zhang C, Lu L.
europepmc +1 more source
Bacterial fumarase and L-malic acid are evolutionary ancient components of the DNA damage response. [PDF]
Singer E +3 more
europepmc +1 more source
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Spectroscopic Studies of Lanthanide(III) Complexes with L-Malic Acid in Binary Systems. [PDF]
Zabiszak M +3 more
europepmc +1 more source
Toward understanding the key enzymes involved in β-poly (L-malic acid) biosynthesis by Aureobasidium pullulans ipe-1. [PDF]
Yu H +5 more
europepmc +1 more source

