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Microbial Biosynthesis of L-Malic Acid and Related Metabolic Engineering Strategies: Advances and Prospects

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical industries. As an intermediate of the TCA cycle, malic acid is one of the most promising building block chemicals that can be produced from renewable sources ...
Zhen Wei   +7 more
doaj   +1 more source

Identifying the best parameters to determine genotype capability to retain adequate malic acid at harvest and in final wines

open access: yesOENO One, 2023
Maintaining optimal grape acidity at harvest is one of the most complicated challenges under climate change pressures, especially in early ripening cultivars. Warming trends are compressing vine phenology and fostering berry malic acid respiration.
Tommaso Frioni   +5 more
doaj   +1 more source

Differences in Microbial Communities Stimulated by Malic Acid Have the Potential to Improve Nutrient Absorption and Fruit Quality of Grapes

open access: yesFrontiers in Microbiology, 2022
Malic acid is a component of the rhizosphere exudate and is vital for crop growth. However, little information is available about the effects of external applications of malic acid on the nutrient absorption and quality of grape fruit, and few studies ...
Peng Si   +6 more
doaj   +1 more source

Contaminant of malic acid: A malic enzyme inhibitor [PDF]

open access: yesFEBS Letters, 1971
A sample of malic acid (Mann Laboratories, C.P. grade, Lot #S 1090) strongly inhibited the malic enzyme activity of a pig adipose tissue supernatant fraction (100,000 g), as measured by the method of Ochoa [l] . Thin-layer cellulose chromatography (Brinkmann MN-Polygram Cel-300-Ecteola) using diethyl ether-formic acid-Hz0 (7:2:1) as mobile phase ...
Anderson, D.B.   +2 more
openaire   +2 more sources

Physical, Chemical, and Sensory Properties of Robusta Coffee Effervescent Tablets Formulated in Various Organic Acids

open access: yesCoffee and Cocoa Research Journal, 2022
Coffee effervescent products are an innovation in coffee formulation. The compounds that play a role in effervescent are acids and bases. Type of organic acid give an impact on the effervescent characteristics.
Umar Hafidz Asy'ari Hasbullah   +3 more
doaj   +1 more source

Enhanced l-Malic Acid Production by Aspergillus oryzae DSM 1863 Using Repeated-Batch Cultivation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
l-Malic acid is a C4-dicarboxylic acid and a potential key building block for a bio-based economy. At present, malic acid is synthesized petrochemically and its major market is the food and beverages industry.
Vanessa Schmitt   +2 more
doaj   +1 more source

Malic Acid Production by Aspergillus Oryzae: the Effect of Alkaline-earth Carbonate Buffer Identity

open access: yesChemical Engineering Transactions, 2022
Malic acid is a specialty chemical that is currently mainly used in the food and beverage industry (market value of $182 million) but has a potential market value of $3.5 billion if used to produce maleic anhydride.
Hendrik Brink   +2 more
doaj   +1 more source

Anticarcinogenic properties of malic acid on glioblastoma cell line through necrotic cell death mechanism

open access: yesMANAS: Journal of Engineering, 2021
This study aimed to investigate the anticarcinogenic and genotoxic damage potentials of malic acid on human fibroblast cells (HDFa) and glioblastoma (U87-MG) cell lines.
Mehmet Enes Arslan
doaj   +1 more source

Effects of Dietary L-malic Acid Supplementation on Meat Quality, Antioxidant Capacity and Muscle Fiber Characteristics of Finishing Pigs

open access: yesFoods, 2022
L-malic acid is a vital intermediate in the citric acid cycle and has been reported to improve the antioxidant capacity and aerobic oxidation of weaned piglets; however, its application in finishing pigs is limited at present.
Enfa Yan   +5 more
doaj   +1 more source

Microbial Production of Malic Acid from Biofuel-Related Coproducts and Biomass

open access: yesFermentation, 2017
The dicarboxylic acid malic acid synthesized as part of the tricarboxylic acid cycle can be produced in excess by certain microorganisms. Although malic acid is produced industrially to a lesser extent than citric acid, malic acid has industrial ...
Thomas P. West
doaj   +1 more source

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