L-Tryptophan Stimulates Bioactive Metabolite Accumulation and Cell Wall Remodelling in Flax Callus Cultures [PDF]
MoleculesWhile L-tryptophan is a precursor of plant growth regulators, its effects on secondary metabolism, amino acid profile and cell wall organization in flax callus remain underexplored.
Kornelia L. Tudruj +4 more
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A comprehensive review and comparison of L-tryptophan biosynthesis in Saccharomyces cerevisiae and Escherichia coli [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 L-tryptophan and its derivatives are widely used in the chemical, pharmaceutical, food, and feed industries. Microbial fermentation is the most commonly used method to produce L-tryptophan, which calls for an effective cell factory.
Xinru Ren +8 more
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Frontiers in Sustainability, 2022 L-tryptophan is a naturally occurring α-amino acid that is also purchased by consumers for medicinal and dietary purposes. L-tryptophan is also a starting point for synthesizing medical derivatives with antiplatelet aggregation and antibacterial activity.
Alan Overcash +6 more
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Dietary L-tryptophan supplementation alleviates ammonia-induced stress in Nile tilapia fingerlings [PDF]
Scientific ReportsL-tryptophan dietary supplementation is a useful tactic to increase aquatic animals’ energy stores and antioxidant capability, thereby enhancing their resistance to environmental stressors like ammonia stress.
Eman Y. Mohammady +4 more
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Genetic regulation of l-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis [PDF]
Fungal Biology and BiotechnologyBackground Although Basidiomycota produce pharmaceutically and ecologically relevant natural products, knowledge of how they coordinate their primary and secondary metabolism is virtually non-existent.
Paula Sophie Seibold +5 more
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Safety and efficacy of a feed additive consisting of l‐tryptophan produced with Corynebacterium glutamicum KCCM 80346 for all animal species (CJ Europe GmbH) [PDF]
EFSA JournalFollowing a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l‐tryptophan produced by fermentation with a genetically modified strain of Corynebacterium ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
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Effects of Prepartum L-Tryptophan Supplementation on the Postpartum Performance of Holstein Cows [PDF]
AnimalsThe negative energy balance occurring in the periparturient period of cows will impede their health and postpartum performance. To target this issue, L-tryptophan was supplied to the prepartum cows.
Xuening Liu +9 more
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Novel L-tryptophan-functionalized zirconium dioxide nanoparticles catalysed one-pot and solvent-free synthesis of 2 H-indazolo [2, 1-b] phthalazine-triones [PDF]
Scientific ReportsZirconia nanoparticles modified with L-tryptophan (ZrO₂@L-Try) demonstrate increased biocompatibility and catalytic activity by capitalizing on the bioactive properties of L-tryptophan, a crucial amino acid known for its role in protein synthesis and ...
Ali Kareem Abbas +2 more
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Scientific Opinion on the safety and efficacy of L-tryptophan technically pure produced by fermentation with Escherichia coli for all animal species, based on a dossier submitted by HELM AG on behalf of Global Bio-Chem Technology [PDF]
EFSA Journal, 2014 The product L-tryptophan is a feed additive produced by fermentation with a genetically modified (GM) strain of Escherichia coli. The amino acid L-tryptophan itself is considered safe for the target animals, the consumer and the environment. However, the
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
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Influence of tryptophan contained in 1-Methyl-Tryptophan on antimicrobial and immunoregulatory functions of indoleamine 2,3-dioxygenase. [PDF]
PLoS ONE, 2012 Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregulatory effector molecule essential for the establishment of tolerance by regulating local tryptophan (Trp) concentrations.
Silvia K Schmidt +7 more
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