Results 181 to 190 of about 51,633,057 (277)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Économie de l\u27immatériel : la croissance de demain (L\u27) [PDF]

Rapport au ministre de l\u27Economie, des Finances et de l\u27Industrie - Analyse de l\u27économie de l\u27immatériel comme économie en gestation au fort potentiel de croissance : économie de la connaissance, systémique et fonctionnant en réseau, se ...
Jouyet, Jean-Pierre
core  

Deacetyl Ophiopojaponin A ameliorates Asthma by Inhibiting L-Type Calcium Channel Cav2.3 to Reduce Calcium Load in Airway Epithelial Cells. [PDF]

J Inflamm Res
Li H, Jiang L, Qian J, Bao W, Huang K, Li D, Zhang A, Sun J, Lu J, Wei D.   +9 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

THE CALCIUM CHANNEL PORE IS SMALLER IN T-TYPE THAN IN L-TYPE CHANNELS.

, 2001
ORAL COMMINICATION@ A NATIONAL MEETING The study explores the size of T-type channel pore by comparing the permeability of the different isoforms of these channels and of L-type channels to progressively bulkier organic cations.
CATALDI, MAURO
core  

L-type voltage-gated Ca²⁺ channels control T cell killing via non-canonical Hedgehog signalling. [PDF]

EMBO Rep
Beke F, Hanna J, Kapeni C, Carbonaro V, Mueller N, Trotter S, Chilamakuri C, O'Brien LM, de la Roche M.   +8 more
europepmc   +1 more source

Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels

Proceedings of the National Academy of Sciences of the United States of America, 2012
R. Dixon, Can Yuan, Edward P. Cheng, Manuel F. Navedo, L. Santana   +4 more
semanticscholar   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Adolescent presentation of L-type ccTGA with pulmonary valve hypoplasia and RV dysfunction: from cardiogenic shock to surgical repair. [PDF]

Egypt Heart J
Jain S, Kumar D, Kumar N, Shrivastava PM.   +3 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source