Results 111 to 120 of about 180,512 (263)

Calcium channel blocker poisoning

Zdravniški Vestnik, 2005
Background: Calcium channel blockers act at L-type calcium channels in cardiac and vascular smooth muscles by preventing calcium influx into cells with resultant decrease in vascular tone and cardiac inotropy, chronotropy and dromotropy.
Miran Brvar, Hugon Možina, Martin Možina, Matjaž Bunc   +3 more
doaj  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

L-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: Implications for substance use, mood disorders and co-morbidities. [PDF]

Neuropharmacology, 2023
Nunes EJ, Addy NA.
europepmc   +1 more source

Additional file 3: Fig S3. of Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells

, 2017
Yu‐Guang Ma, Junwei Wang, Yungang Bai, Mei Liu, Man‐Jiang Xie, Zhijun Dai   +5 more
openalex   +1 more source

Kinetic modulation of guinea‐pig cardiac L‐type calcium channels by fendiline and reversal of the effects of Bay K 8644 [PDF]

, 1992
Wolfgang Schreibmayer, O Tripathi, H. A. Tritthart   +2 more
openalex   +1 more source

Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current

Channels
L-type calcium channels are essential for the excitation-contraction coupling in cardiac muscle. The CaV1.2 channel is the most predominant isoform in the ventricle which consists of a multi-subunit membrane complex that includes the CaV1.2 pore-forming ...
Felipe Arancibia, Daniela De Giorgis, Franco Medina, Tamara Hermosilla, Felipe Simon, Diego Varela   +5 more
doaj   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Renal Function in Hypertensive Patients Receiving Cilnidipine and L-Type Calcium Channel Blockers: A Meta-Analysis of Randomized Controlled and Retrospective Studies. [PDF]

Cureus, 2022
Srivathsan M, Vardhan V, Naseem A, Patil S, Rai V, Langade DG.   +5 more
europepmc   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source

Rad-GTPase contributes to heart rate via L-type calcium channel regulation. [PDF]

J Mol Cell Cardiol, 2021
Levitan BM, Ahern BM, Aloysius A, Brown L, Wen Y, Andres DA, Satin J.   +6 more
europepmc   +1 more source