Results 121 to 130 of about 180,512 (263)

Effects of Cilnidipine, an L/N-Type Calcium Channel Blocker, on Carotid Atherosclerosis in Japanese Post-Stroke Hypertensive Patients: Results from the CA-ATTEND Study

, 2017
Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Norihiro Suzuki, Tsukasa Teshima, Hitoshi Sugii, Shinobu Nagahama, Yoshiki Kurose, Hirofumi Maruyama, Masayasu Matsumoto   +9 more
openalex   +2 more sources

The Neuronal β4 Subunit Increases the Unitary Conductance of L-type Voltage-gated Calcium Channels in PC12 Cells [PDF]

, 2003
Jessica M. Schjött, Shu-Chan Hsu, Mark R. Plummer   +2 more
openalex   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca²⁺ through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation. [PDF]

Nutrients, 2023
Zheng Q, He Y, Li L, Rui C, Li N, Zhang Y, Ye Y, Zhang Z, Yang X, Tang J, Xu Z.   +10 more
europepmc   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

A Novel High Content Angiogenesis Assay Reveals That Lacidipine, L-Type Calcium Channel Blocker, Induces In Vitro Vascular Lumen Expansion. [PDF]

Int J Mol Sci, 2022
Nawrot DA, Ozer LY, Al Haj Zen A.
europepmc   +1 more source

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

Advanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman, Bryan Guo, William W. Du, Burton Yang, Yu Sun, Lidan You   +5 more
wiley   +1 more source

Alterations of Dopamine Receptors and the Adaptive Changes of L-Type Calcium Channel Subtypes Regulate Cocaine-Seeking Habit in Tree Shrew. [PDF]

Life (Basel), 2022
Duan Y, Jin L, Du W, Jin S, Meng Y, Li Y, Zhang J, Liang J, Sui N, Shen F.   +9 more
europepmc   +1 more source

L-type calcium channels are involved in mediating the anti-inflammatory effects of magnesium sulphate [PDF]

, 2009
Chien‐Yu Lin, Pei Tsai, Yi-Wei Hung, Chun‐Jen Huang   +3 more
openalex   +1 more source

Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating

Advanced Biology, EarlyView.
This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake, Masaya Shimabukuro, Masahiko Terauchi, Eriko Marukawa, Masakazu Kawashita   +4 more
wiley   +1 more source