Results 171 to 180 of about 515,300 (403)
MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY
Arthritis Care &Research, Accepted Article.Objective
Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of SPRING collaborators +77 morewiley +1 more sourceBack cover: Quercetin Attenuates Ethanol‐Induced Iron Uptake and Myocardial Injury by Regulating the Angiotensin II‐L‐Type Calcium Channel [PDF]
, 2018 Xiaoping Guo, Man Chen, Hongmei Zeng, Peiyi Liu, Xinghong Zhu, Feng Zhou, Jingjing Liu, Jun Zhang, Zhuangzhuang Dong, Yuhan Tang, Chao Gao, Ping Yao +11 moreopenalex +1 more sourceNew Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Arthritis Care &Research, Accepted Article.Objective
Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high magnitude stress.Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium +15 morewiley +1 more sourceHalf-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel CaV1.2. [PDF]
J Biol Chem, 2022 Bartels P, Salveson I, Coleman AM, Anderson DE, Jeng G, Estrada-Tobar ZM, Man KNM, Yu Q, Kuzmenkina E, Nieves-Cintron M, Navedo MF, Horne MC, Hell JW, Ames JB. +13 moreeuropepmc +1 more sourceβ‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia +11 morewiley +1 more sourceDifferential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence
Neuropsychopharmacology, 2017 Stefanie Uhrig, D. Vandael, A. Marcantoni, N. Dedic, A. Bilbao, M. Vogt, Natalie Hirth, Laura Broccoli, R. E. Bernardi, K. Schönig, P. Gass, D. Bartsch, R. Spanagel, J. Deussing, W. Sommer, E. Carbone, A. Hansson +16 moresemanticscholar +1 more sourceModulation of L-Type (CaV1.3) Calcium Channels
, 2005 L-type CaV1.3 calcium channels perform critical functions in auditory hair cells, cardiac pacemaker cells, and pancreatic β-cells, but little is currently known about how these channels are modulated by cell signaling mechanisms. To begin to address this issue, we have tested the ability of various G protein-coupled receptors (GPCRs) to modulate CaV1.3 openaire +3 more sources