Results 11 to 20 of about 515,300 (403)
Calcium channel L-type; calcium channel voltage-dependent L type α1D subunit (CACNA1D; Cav1.3) [PDF]
Science-Business eXchange, 2010 openalex +3 more sources
Denitration of L‐type calcium channel [PDF]
FEBS Letters, 2008 Tyrosine nitration results in altered function of selective proteins, including human smooth muscle L‐type calcium channel, hCav1.2b. We report here that Cav1.2 is also subject to “denitration”. Cell lysates from activated macrophage‐like cell line, RAW264.7 cells, reversed peroxynitrite‐induced nitration of the carboxy terminus of Cav1.2 in a 1D gel ...
Kang, Minho, Akbarali, Hamid I.
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Psychostimulants, L-type Calcium Channels, Kinases, and Phosphatases [PDF]
The Neuroscientist, 2005 There is growing evidence for the role of voltage-gated L-type Ca2+ channels in mediating aspects of the addictive properties of psychostimulants. L-type Ca2+ channels activate Ca2+ second-messenger pathways that regulate protein phosphorylation and thereby activation of target gene expression.
Anjali M. Rajadhyaksha +1 more
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L-Type Calcium Channel C Terminus Autoregulates Transcription [PDF]
Circulation Research, 2009 Calcium homeostasis is critical for cardiac myocyte function and must be tightly regulated. The guiding hypothesis of this study is that a carboxyl-terminal cleavage product of the cardiac L-type calcium channel (Ca V 1.2) autoregulates expression. First, we confirmed that the Ca
E. Schroder, Miranda J. Byse, J. Satin
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Autoregulation of Cardiac l-Type Calcium Channels [PDF]
Trends in Cardiovascular Medicine, 2009 l-Type calcium channels (LTCCs) are major contributors to electrical and contractile function of the heart. They regulate action potential duration, enable calcium entry into cardiac myocytes for contraction, and regulate growth-related signaling in the heart.
Jonathan, Satin, Elizabeth A, Schroder
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Tissue-specific expression of calcium channels [PDF]
, 1993 The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Biel +59 more
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Journal of Cell Biology, 1993 To identify and localize the protein products of genes encoding distinct L-type calcium channels in central neurons, anti-peptide antibodies specific for the class C and class D alpha 1 subunits were produced.
J. Hell +7 more
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Translational Neuroscience, 2022 The CACNA1C protein is a L-type calcium channel, which influence affective disorders.
Dam Henrik +4 more
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Functional Importance of L- and P/Q-Type Voltage-Gated Calcium Channels in Human Renal Vasculature [PDF]
, 2011 Calcium channel blockers are widely used for treatment of hypertension, because they decrease peripheral vascular resistance through inhibition of voltage-gated calcium channels.
Cribbs, Leanne L +6 more
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JACC: Basic to Translational Science, 2016 Heterozygous mice (αMHC403/+) expressing the human disease-causing mutation Arg403Gln exhibit cardinal features of hypertrophic cardiomyopathy (HCM) including hypertrophy, myocyte disarray, and increased myocardial fibrosis.
Helena M. Viola, PhD +9 more
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