Results 221 to 230 of about 180,512 (263)

Differential splicing patterns of L-Type calcium channel Cav1.2 subunit in hearts of Spontaneously Hypertensive Rats and Wistar Kyoto rats

, 2007
Zhen Zhi Tang, Ping Liao, Guang Li, Feng Jiang, Dejie Yu, Xin Hong, Tan Yong, Gregory Tan, Songqing Lu, Jing Wang, Tuck Wah Soong   +10 more
openalex   +2 more sources

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

An N-/L-type calcium channel blocker, cilnidipine, suppresses autonomic, electrical, and structural remodelling associated with atrial fibrillation. [PDF]

Cardiovasc Res, 2019
Tajiri K, Guichard JB, Qi X, Xiong F, Naud P, Tardif JC, Costa AD, Aonuma K, Nattel S.   +8 more
europepmc   +1 more source

Fluorophobic Effect Enables Selective Detection of PFAS in Water with Electrolyte‐Gated Organic Transistors

Advanced Functional Materials, EarlyView.
PerFluoroAlkyl Substances (PFAS) are responsible of major and persistent environmental pollution worldwide. This work demonstrates an ultra‐sensitive sensor for PFAS based on an organic transistor whose gate is functionalized with a binary self‐assembled monolayer containing a perfluorinated molecule.
Rian Zanotti, Marcello Berto, Matteo Sensi, Alessandro Paradisi, Eleonora Veronese, Lucia Pasquato, Carlo Augusto Bortolotti, Pierangelo Metrangolo, Fabio Biscarini   +8 more
wiley   +1 more source

Mutations in voltage-gated L-type calcium channel: implications in cardiac arrhythmia. [PDF]

Channels (Austin), 2018
Zhang Q, Chen J, Qin Y, Wang J, Zhou L.
europepmc   +1 more source

Artificial Intelligence‐Driven Development in Rechargeable Battery Materials: Progress, Challenges, and Future Perspectives

Advanced Functional Materials, EarlyView.
AI is transforming the research paradigm of battery materials and reshaping the entire landscape of battery technology. This comprehensive review summarizes the cutting‐edge applications of AI in the advancement of battery materials, underscores the critical challenges faced in harnessing the full potential of AI, and proposes strategic guidance for ...
Qingyun Hu, Junyuan Lu, Jian Hui, Ziyuan Rao, Yang Ren, Hong Wang   +5 more
wiley   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

Advanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran, Anton Maraldo, Chi Cong Nguyen, Trinh Thi‐Phuong Ho, Lauryn Srethbhakdi, Habib Joukhdar, Quinn van Hilst, Syamak Farajikhah, Fariba Dehghani, Thanh Nho Do, Khoon S. Lim, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains. [PDF]

Front Physiol, 2018
Wright PT, Sanchez-Alonso JL, Lucarelli C, Alvarez-Laviada A, Poulet CE, Bello SO, Faggian G, Terracciano CM, Gorelik J.   +8 more
europepmc   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase increases Ca²⁺ currents by interacting with Ca_v1.2 and reducing intrinsic inactivation of the L-type calcium channel.

Am J Physiol Heart Circ Physiol, 2020
Gupte R, Dhagia V, Rocic P, Ochi R, Gupte SA.   +4 more
europepmc   +1 more source