Results 311 to 320 of about 515,300 (403)

The IVS6 segment of the L‐type calcium channel is critical for the action of dihydropyridines and phenylalkylamines.

EMBO Journal, 1996
A. Schuster, Ľ. Lacinová, N. Klugbauer, H. Ito, L. Birnbaumer, F. Hofmann   +5 more
semanticscholar   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes

Diabetologia, 2013
T. Reinbothe, Sami Alkayyali, E. Ahlqvist, T. Tuomi, B. Isomaa, V. Lyssenko, E. Renström   +6 more
semanticscholar   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Enhanced Expression of L-type Cav1.3 Calcium Channels in Murine Embryonic Hearts from Cav1.2-deficient Mice

, 2003
Man Xu, Andrea Welling, Susanne Paparisto, Franz Hofmann, Norbert Klugbauer   +4 more
openalex   +1 more source

Angiotensin II Increases Expression of α1C Subunit of L-Type Calcium Channel Through a Reactive Oxygen Species and cAMP Response Element–Binding Protein–Dependent Pathway in HL-1 Myocytes

, 2007
Chia-Ti Tsai, Danny L Wang, Wen‐Pin Chen, Juey-Jen Hwang, Chia-Shan Hsieh, K. Hsu, C. Tseng, L. Lai, Y. Tseng, F. Chiang, Jiunn-lee Lin   +10 more
semanticscholar   +1 more source

Ca2+–calmodulin‐dependent protein kinase II represses cardiac transcription of the L‐type calcium channel α1C‐subunit gene (Cacna1c) by DREAM translocation

Journal of Physiology, 2011
Jarkko J Ronkainen, S. L. Hänninen, T. Korhonen, Jussi T. Koivumäki, R. Skoumal, Sini Rautio, Veli-Pekka Ronkainen, P. Tavi   +7 more
semanticscholar   +1 more source

Quantifying Spatio‐Operational Heterogeneity in Electrochemical Devices via Operando Correlative Neutron and X‐Ray Tomography

Advanced Functional Materials, EarlyView.
Heterogeniety in electrochemical systems heavily influences device performance and durability. The study shows unique evidence of spatio‐operational heterogeneity in fuel cells via operando neutron and X‐ray tomography. Large variations in membrane thickness and hydration depend upon location and operating conditions, with implications on membrane ...
Pranay Shrestha, Jacob M. LaManna, Kieran F. Fahy, ChungHyuk Lee, Pascal J. Kim, Jason K. Lee, Elias Baltic, Daniel S. Hussey, David L. Jacobson, Aimy Bazylak   +9 more
wiley   +1 more source

The L-type calcium channel current modulation mechanism: the plot thickens and fogs. [PDF]

J Clin Invest, 2019
Ahern BM, Satin J.
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source