Results 341 to 350 of about 515,300 (403)

Self‐Trapped Hole Migration and Defect‐Mediated Thermal Quenching of Luminescence in α‐ and β‐Ga2O3

open access: yesAdvanced Functional Materials, EarlyView.
Temperature‐dependent photoluminescence and first‐principles calculations reveal self‐trapped hole migration as the microscopic origin of thermal quenching in α‐ and β‐Ga2O3. The low migration barrier in α‐Ga2O3 enables defect trapping and enhances blue luminescence, while the higher barrier in β‐Ga2O3 preserves ultraviolet emission at elevated ...
Nima Hajizadeh   +11 more
wiley   +1 more source

Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization

open access: yesAdvanced Functional Materials, EarlyView.
Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao   +12 more
wiley   +1 more source

L-Type Calcium Channels: Structure and Functions

open access: yes, 2018
Feng, Tianhua   +2 more
openaire   +3 more sources

Precursor Mineral Phases of Forming Mollusk Shell Nacre: A Study of Hydrated Samples

open access: yesAdvanced Functional Materials, EarlyView.
Mineral, organic phase, and water are the essential components in mollusk shell nacre formation. Their interplay is not well understood, because the hydrated material is difficult to observe at high resolution, under close to native conditions. Forming nacre is studied using environmental and cryo‐electron microscopy and hydrated ACC phases, together ...
Anna Kozell   +4 more
wiley   +1 more source

L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence

Pharmacological Reviews, 2021
This review describes interactions between compounds, primarily dihydropyridines, that block L-type calcium channels and drugs that cause dependence, and the potential importance of these interactions.
H. Little
semanticscholar   +1 more source

Assays for L-type voltage gated calcium channels

Analytical Biochemistry, 2022
Voltage gated calcium channels (VGCCs) are pursued as drug targets for neurodegenerative and cardiovascular diseases. High throughput drug screening targeting VGCCs depends on patch-clamp electrophysiology or fluorophore-based calcium imaging that requires powerful equipment and specialized expertise thus leading to cost escalation.
G.M. Archana   +2 more
openaire   +2 more sources

L-Type Calcium Channel Disease

2008
In recent years, the progress of molecular genetics of inherited arrhythmogenic diseases portrays an unexpected complexity of clinical phenotypes associated with mutations in several genes that control cardiac excitability. Among the most recent findings, the voltage-gated L-type cardiac calcium channel (Cav1.2) has been involved in the pathogenesis of
Ruan Y   +3 more
openaire   +1 more source

L-Type Calcium Channels: The Low Down

Journal of Neurophysiology, 2004
L-type calcium channels couple membrane depolarization in neurons to numerous processes including gene expression, synaptic efficacy, and cell survival. To establish the contribution of L-type calcium channels to various signaling cascades, investigators have relied on their unique pharmacological sensitivity to dihydropyridines.
Diane, Lipscombe   +2 more
openaire   +2 more sources

L-Type Calcium Channels

Current Pharmaceutical Design, 2006
The Ca2+ channel blockers represent a successful group of therapeutic agents directed against cardiovascular targets, including hypertension and angina. These drugs, including the first-generation verapamil, nifedipine and diltiazem are directed against a subclass of voltage-gated Ca2+ channel - the L-type channel.
openaire   +2 more sources

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