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Calcium Signaling in Mast Cells: Focusing on L-Type Calcium Channels
2012Mast cells play central roles in adaptive and innate immunity. IgE-dependent stimulation of the high-affinity IgE receptor (FcεRI) results in rapid secretion of various proinflammatory chemical mediators and cytokines. All of the outputs depend to certain degrees on an increase in the intracellular Ca(2+) concentration, and influx of Ca(2+) from the ...
Yoshihiro, Suzuki +2 more
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Interaction of the L-Type Calcium Channel with Calcium Channel Blockers
1996The contribution of the primary structure and the β subunit to the block of the L-type α1C calcium channel was studied. The α1C-a and the α1C-b subunits were truncated at aa 1733 and 1728, respectively, and were expressed stably in human embryonic kidney (HEK) 293 cells (α1C-at and α1C-bt cell line). The β3 subunit was coexpressed stably with the α1C-a
Franz Hofmann +5 more
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An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness
Nature Genetics, 1998T. Strom +14 more
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Local calcium transients triggered by single L-type calcium channel currents in cardiac cells.
Science, 1995Jose Ramon +3 more
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L-type calcium channel structure and function
1996The frequency and force of contraction of the heart is primarily controlled by an influx of calcium across the cell membrane during the action potential. The best characterized pathway for calcium entry in atrial and ventricular cells are voltage-dependent calcium channels. Cardiac myocytes contain two types of voltage-dependent calcium channels, the T-
Franz Hofmann, Martin Biel
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Plasticity of Neuronal L‐Type Calcium Channels
Annals of the New York Academy of Sciences, 1988Govoni, S +5 more
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L-Type Calcium Channels and Adrenomedullary Secretion
1988On the basis that the calcium removal from solutions perfusing cat adrenal glands abolished acetylcholine-evoked catecholamine release, and that acetylcholine caused some increase in membrane permeability to common species of ions including Ca, particularly at the muscle end-plate (Del Castillo and Katz, 1956), Douglas and Rubin (1961) coined the ...
C. R. Artalejo +4 more
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Artificial channels for confined mass transport at the sub-nanometre scale
Nature Reviews Materials, 2021Jie Shen, Gong-Ping Liu, Yu Han
exaly