Results 221 to 230 of about 1,771,262 (308)

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell   +6 more
wiley   +1 more source

Intestinal ultrasound versus magnetic resonance enterography for detecting small bowel Crohn's disease in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives In Crohn's disease (CD), magnetic resonance enterography (MRE) is used to assess small bowel disease activity. Intestinal ultrasound (IUS) is a less invasive, cheaper and more easily accessible imaging modality in CD. This study assesses the diagnostic accuracy of IUS versus MRE and defines an optimal bowel wall thickness (BWT) cut ...
Johanna M. B. W. Vos   +11 more
wiley   +1 more source

Plasmid-encoded Pgp3 protein enhances the infectivity of <i>Chlamydia trachomatis</i> serovar L2 in mice. [PDF]

open access: yesZhong Nan Da Xue Xue Bao Yi Xue Ban
Sun X   +5 more
europepmc   +1 more source

Models of DG‐Carbon Bands in Raman Spectra: Effects of Basis Functions and Initial Values on the Uniqueness and S/N of Fits Obtained for Atmospheric Aerosol Using Automated Methods

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectra containing D/G features are fit using combinations of basis functions and initial conditions. Fits with two Lorentzian functions converged to a single optimized fit even with variation of initial peak positions. For five‐band fits, sometimes the final fit varied with initial conditions, and constraints on peak center position were ...
David C. Doughty, Steven C. Hill
wiley   +1 more source

Ultrasound Features Associated with Activity of Perianal Fistulas in Pediatric Patients with Crohn's Disease

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives To evaluate the usefulness of transperineal ultrasonography (TPUS) for assessing the activity of perianal fistulas by exploring features associated with the magnetic resonance novel index for fistula imaging in Crohn's disease (MAGNIFI‐CD).
Ok Jeong Yu   +10 more
wiley   +1 more source

Diffraction‐Free Natural Optical Skyrmions and Their Subwavelength Confinement Around Vortices

open access: yesLaser &Photonics Reviews, EarlyView.
ABSTRACT Diffraction causes waves to spread out as they propagate freely. The tighter the lateral confinement, the faster the spreading. Past research on how to suppress diffraction has been based on wave engineering and has led so far to idealized waves that, in real settings, eventually diffract.
Nilo Mata‐Cervera   +4 more
wiley   +1 more source

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