Results 1 to 10 of about 206,009 (155)

Species variation in the cartilaginous endplate of the lumbar intervertebral disc. [PDF]

open access: yesJOR Spine, 2022
Species variation in the CEP of lumbar IVDs was determined based on histology and SEM analysis. The integration of BEP‐CEP in humans, pigs, goats, and rabbits was mainly achieved by the collagen bundles anchoring system, while the typical BEP‐CEP interface did not exist in rats.
Li YH   +8 more
europepmc   +2 more sources

Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer. [PDF]

open access: yesAdv Sci (Weinh)
Dysregulated eukaryotic elongation factor 2 kinase (eEF2K) expression is implicated in the pathogenesis of triple‐negative breast cancer (TNBC). Compound C1 is designed and synthesized, which shows potent activity in degrading eEF2K protein. C1 significantly inhibits the proliferation and metastasis of TNBC.
Zhong C   +12 more
europepmc   +2 more sources

Connected speech in EFL pedagogy

open access: yesForum Pedagogiczne, 2022
Teaching BATNA and WATNA on EFL – English as a Foreign Language - programmes involves the development of students’ competence in a foreign language and the improvement of their negotiation skills and their ability to analyse cases. This article presents
Piotr Jednaszewski
doaj   +1 more source

FUNKCJONOWANIE KOMUNIKACYJNE I SPOŁECZNE DZIECKA/UCZNIA ZE SPEKTRUM ZABURZEŃ AUTYSTYCZNYCH (ASD) I DZIECKA/UCZNIA Z MUTYZMEM WYBIÓRCZYM (MW) – PODOBIEŃSTWA I RÓŻNICE

open access: yesForum Pedagogiczne, 2023
Autyzm i mutyzm, chociaż mają wspólne komponenty (por. np. trudności z werbalnym komunikowaniem się, problemy w nawiązywaniu interakcji społecznych, trudności z kontaktem wzrokowym, nadwrażliwość na dotyk czy dźwięk), to stanowią dwa odmienne ...
Renata Marciniak-Firadza
doaj   +1 more source

Towards Platinum(II) Complexes for in cellulo Applications: Synthesis, Characterization, Biological and Catalytic Evaluation

open access: yesHelvetica Chimica Acta, Volume 106, Issue 8, August 2023., 2023
Abstract With the aim of achieving bioorthogonal intracellular catalysis, a library of platinum(II) complexes was synthesized. Their non‐toxicity to living cells was demonstrated and their catalytic activity was evaluated on a cyclization reaction leading to a highly fluorescent coumarin. None of the platinum complexes showed any catalytic activity for
Lisa Gourdon‐Grünewaldt   +6 more
wiley   +1 more source

Seniors during the COVID-19 pandemic

open access: yesForum Pedagogiczne, 2022
The time of the pandemic was a time of crisis for the whole world. Young people lost their jobs, they were prevented from implementing their plans, and their social contacts were drastically limited. The article, however, focuses on seniors, for whom it
Anna Seredyńska
doaj   +1 more source

Synthesis of Geminal Bis‐ and Tetrakisphosphonate Ester Derivatives and Their Coordination Behavior Towards Ca(II) Ions

open access: yesEuropean Journal of Inorganic Chemistry, Volume 2022, Issue 17, June 17, 2022., 2022
Geminal Bisphosphonate (BP) Esters in Ca(II) Ion Coordination. A series of geminal BPs was prepared starting from their corresponding ethyl‐ or isopropyl (arylmethylene)phosphonate ester precursors. Complexation with CaCl2 yields the derived coordination compounds [Ca(H2O)2(L1–L3)2]Cl2 or [Ca(L8)Cl2]n.
Ingo Koehne, Rudolf Pietschnig
wiley   +1 more source

Mathematical Modelling of the Spatial Epidemiology of COVID‐19 with Different Diffusion Coefficients

open access: yesInternational Journal of Differential Equations, Volume 2022, Issue 1, 2022., 2022
This paper addresses the discrepancy between model findings and field data obtained and how it is minimized using the binning smoothing techniques: means, medians, and boundaries. Employing both the quantitative and the qualitative methods to examine the complex pattern involved in COVID‐19 transmission dynamics reveals model variation and provides a ...
Benedict Barnes   +7 more
wiley   +1 more source

Prawość i cnoty pokrewne. Reaktywacja cnót istotnych w procesie wychowania moralnego

open access: yesForum Pedagogiczne, 2020
Prawość, choć stanowi rdzenną kategorię deontologii i aretologii, relatywnie rzadko staje się przedmiotem badań przedstawicieli pedagogiki. W ramach szerszych badań dotyczących ludzkiej prawości, w niniejszym artykule zaprezentowano ujęcie tej kategorii
Alicja Żywczok
doaj   +1 more source

Kryzys (w) edukacji i jego przezwyciężenie według Jana Amosa Komeńskiego i Emanuela Rádla

open access: yesForum Pedagogiczne, 2020
Wychowanie i kształcenie są współcześnie pogrążone w głębokim kryzysie. Żeby zrozumieć jego istotę i możliwości przezwyciężenia, autorka odwołuje się do myśli Jana Amosa Komeńskiego i Emanuela Rádla.
Naděžda Pelcová
doaj   +1 more source

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