Results 1 to 10 of about 212,612 (155)
Species variation in the cartilaginous endplate of the lumbar intervertebral disc. [PDF]
JOR Spine, 2022 Species variation in the CEP of lumbar IVDs was determined based on histology and SEM analysis. The integration of BEP‐CEP in humans, pigs, goats, and rabbits was mainly achieved by the collagen bundles anchoring system, while the typical BEP‐CEP interface did not exist in rats.
Li YH +8 more
europepmc +2 more sources
Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer. [PDF]
Adv Sci (Weinh)Dysregulated eukaryotic elongation factor 2 kinase (eEF2K) expression is implicated in the pathogenesis of triple‐negative breast cancer (TNBC). Compound C1 is designed and synthesized, which shows potent activity in degrading eEF2K protein. C1 significantly inhibits the proliferation and metastasis of TNBC.
Zhong C +12 more
europepmc +2 more sources
Future Oncology, 2023 Current treatment for patients with metastatic hormone-sensitive prostate cancer (mHSPC) delays disease progression and improves survival, but resistance is inevitable. Additional therapies that prolong survival are needed.
C. Gratzke +8 more
semanticscholar +1 more source
Scientific Reports, 2022 Archaeological and genomic evidence suggest that modern Homo sapiens have roamed the planet for some 300–500 thousand years. In contrast, global human mitochondrial (mtDNA) diversity coalesces to one African female ancestor (“Mitochondrial Eve”) some 145
P. Maier +3 more
semanticscholar +1 more source
Frontiers in Microbiology, 2022 Natural pigments are playing important roles in our daily lives. They not only make products colorful but also provide various health benefits for humans.
Di Meng +4 more
semanticscholar +1 more source
Helvetica Chimica Acta, Volume 106, Issue 8, August 2023., 2023 Abstract With the aim of achieving bioorthogonal intracellular catalysis, a library of platinum(II) complexes was synthesized. Their non‐toxicity to living cells was demonstrated and their catalytic activity was evaluated on a cyclization reaction leading to a highly fluorescent coumarin. None of the platinum complexes showed any catalytic activity for
Lisa Gourdon‐Grünewaldt +6 more
wiley +1 more source
Mathematical Epistemic Beliefs: Through the Gender Lens
Frontiers in Education, 2022 This large survey study set out to ascertain whether gender differences in teachers’ mathematical epistemic beliefs exist, and the extent to which teachers’ gender as well as their teaching experience level, education level, and socio-economic setting of
Natthapoj Vincent Trakulphadetkrai
doaj +1 more source
Frontiers in Veterinary Science, 2021 Protective efficiency of a combination of four recombinant Brucella abortus (B. abortus) proteins, namely outer membrane protein (Omp) 16, Omp19, Omp28, and 50S ribosomal protein L7/L12 was evaluated as a combined subunit vaccine (CSV) against B. abortus
T. X. N. Huy +7 more
semanticscholar +1 more source
European Journal of Inorganic Chemistry, Volume 2022, Issue 17, June 17, 2022., 2022 Geminal Bisphosphonate (BP) Esters in Ca(II) Ion Coordination. A series of geminal BPs was prepared starting from their corresponding ethyl‐ or isopropyl (arylmethylene)phosphonate ester precursors. Complexation with CaCl2 yields the derived coordination compounds [Ca(H2O)2(L1–L3)2]Cl2 or [Ca(L8)Cl2]n.
Ingo Koehne, Rudolf Pietschnig
wiley +1 more source
Mathematical Modelling of the Spatial Epidemiology of COVID‐19 with Different Diffusion Coefficients
International Journal of Differential Equations, Volume 2022, Issue 1, 2022., 2022 This paper addresses the discrepancy between model findings and field data obtained and how it is minimized using the binning smoothing techniques: means, medians, and boundaries. Employing both the quantitative and the qualitative methods to examine the complex pattern involved in COVID‐19 transmission dynamics reveals model variation and provides a ...
Benedict Barnes +7 more
wiley +1 more source