Left Atrial Appendage Closure in Patients Refusing Oral Anticoagulation: The LAAC‐REFUSAL Study [PDF]
Background The benefit of left atrial appendage closure (LAAC) in patients refusing oral anticoagulation (OAC) despite medical recommendations is unknown. We aim to assess the efficacy and the safety of LAAC in patients refusing OAC.
Roberto Galea +11 more
doaj +3 more sources
Impact of Peridevice Leak on Clinical Outcomes After Left Atrial Appendage Closure: The OCEAN‐LAAC Registry [PDF]
Background The impact of peridevice leak (PDL) at device implantation on clinical outcomes after percutaneous left atrial appendage closure (LAAC) is unknown.
Tetsuya Saito +26 more
doaj +4 more sources
Rationale and design of a randomized clinical trial evaluating the efficacy of mechanical neuroprotection in reducing the risk of silent brain infarcts associated with percutaneous left atrial appendage closure: study protocol for a LAAC-SBI trial [PDF]
Background Left atrial appendage closure (LAAC) procedures prevent cardioembolic stroke in patients with atrial fibrillation who have contraindications to oral anticoagulant medications.
Witold Streb +8 more
doaj +4 more sources
Risk Factors and Outcomes of AKI after LAAC Operation: A Single-Center Observational Study from Mainland China [PDF]
Background: This study aimed to investigate the predictors and prognosis of acute kidney injury (AKI) occurrence among Chinese patients following left atrial appendage closure (LAAC).
Lei Zhang +8 more
doaj +2 more sources
Comparison of oral anticoagulation and antiplatelet therapy during the midperiod after percutaneous left atrial appendage closure [PDF]
Background and aimThere is a lack of evidence comparing anticoagulation and antiplatelet therapy during the midperiod time after left atrial appendage closure (LAAC) in clinical practice (the “early period” is defined as “45 days” after LAAC for a single
Chang-Yi Li +8 more
doaj +2 more sources
Long-term outcomes of left atrial appendage closure techniques on stroke prevention of recurrent atrial fibrillation patients: epicardial excision versus percutaneous occlusion [PDF]
ObjectiveThis study aimed to compare the efficacy of left atrial appendage closure performed by excision (LAAC-EE) vs. occlusion (LAAC-PO) for stroke prevention in patients with recurrent atrial fibrillation undergoing radiofrequency ablation.MethodsIn ...
Adnan Abibe Goia, Meng Xu, Hu Qiuming
doaj +2 more sources
Left Atrial Appendage Closure in Patients with Atrial Fibrillation and Intermediate-to-Borderline High Cardiovascular Risk: A Retrospective Propensity Match Cohort Study [PDF]
Background and objective: Evidence of percutaneous left atrial appendage closure (LAAC) and oral anticoagulants (OACs) in non-valvular atrial fibrillation (NVAF) patients with intermediate-to-borderline high stroke risk is scarce. We aimed to compare the
Jiayi Liu +6 more
doaj +2 more sources
Stroke prevention in nonvalvular atrial fibrillation: Thoracoscopic left atrial appendage closure with or without surgical ablationCentral MessagePerspective [PDF]
Objectives: Totally thoracoscopic left atrial appendage closure (TT-LAAC) with or without the MAZE procedure is an LAA management technique that prevents cardioembolic events by closing the LAA in patients with atrial fibrillation (AF).
Hiroshi Ito, MD +5 more
doaj +2 more sources
Management of device embolization following left atrial appendage closure: Two cases and a review of the literature [PDF]
Objectives Device embolization (DE) following left atrial appendage closure (LAAC) is a severe but uncommon complication, and limited data address optimal management strategies for this condition. This review presents two cases of device embolization (DE)
Ahmet Kivrak +8 more
doaj +2 more sources
Percutaneous left atrial appendage closure (LAAC) has been established in clinical practice as an attractive alternative to oral anticoagulation for preventing stroke in patients with atrial fibrillation and high bleeding risk.
Roberto Galea, Lorenz Räber
doaj +1 more source

