Results 91 to 100 of about 6,064,561 (323)

Data from quantitative label free proteomics analysis of rat spleen

open access: yesData in Brief, 2016
The dataset presented in this work has been obtained using a label-free quantitative proteomic analysis of rat spleen. A robust method for extraction of proteins from rat spleen tissue and LC-MS-MS analysis was developed using a urea and SDS-based buffer.
Khadar Dudekula, Thierry Le Bihan
doaj   +1 more source

PhaseStain: the digital staining of label-free quantitative phase microscopy images using deep learning [PDF]

open access: yesLight: Science & Applications, 2018
Using a deep neural network, we demonstrate a digital staining technique, which we term PhaseStain, to transform the quantitative phase images (QPI) of label-free tissue sections into images that are equivalent to the brightfield microscopy images of the
Y. Rivenson   +4 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Label‐free imaging of non‐deparaffinized sections of the human kidney to determine tissue quality and signatures of disease

open access: yesPhysiological Reports, 2022
Label‐free fluorescence imaging of kidney sections can provide important morphological information, but its utility has not been tested in a histology processing workflow.
Angela R. Sabo   +7 more
doaj   +1 more source

Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy [PDF]

open access: yes, 2017
The goal of breast-conserving surgery is to completely remove all of the cancer. Currently, no intraoperative tools can microscopically analyze the entire lumpectomy specimen, which results in 20 to 60% of patients undergoing second surgeries to achieve ...
Aft, Rebecca L   +7 more
core   +3 more sources

Label-free prediction of three-dimensional fluorescence images from transmitted light microscopy

open access: yesNature Methods, 2018
Understanding cells as integrated systems is central to modern biology. Although fluorescence microscopy can resolve subcellular structure in living cells, it is expensive, is slow, and can damage cells.
Chawin Ounkomol   +4 more
semanticscholar   +1 more source

High Throughput Label-Free Enzymatic Assays using Desorption Electrospray Ionization Mass Spectrometry.

open access: yesAngewandte Chemie, 2020
High throughput (HT) enzymatic assays, which typically rely on labeled compounds and plate readers, are important for drug discovery. Mass spectrometry (MS) provides an alternative method of performing HT label-free assays. Here we demonstrate the use of
Nicolás M. Morato   +2 more
semanticscholar   +1 more source

Label free redox capacitive biosensing

open access: yesBiosensors and Bioelectronics, 2013
A surface confined redox group contributes to an interfacial charging (quantifiable by redox capacitance) that can be sensitively probed by impedance derived capacitance spectroscopy. In generating mixed molecular films comprising such redox groups, together with specific recognition elements (here antibodies), this charging signal is able to ...
Fernandes, Flávio C. Bedatty   +3 more
openaire   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Label-Free Biosensors for Cell Biology

open access: yesInternational Journal of Electrochemistry, 2011
Label-free biosensors for studying cell biology have finally come of age. Recent developments have advanced the biosensors from low throughput and high maintenance research tools to high throughput and low maintenance screening platforms.
Ye Fang
doaj   +1 more source

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