Results 41 to 50 of about 6,064,561 (323)

Benchmarking Quantitative Performance in Label-Free Proteomics

open access: yesACS Omega, 2021
Previous benchmarking studies have demonstrated the importance of instrument acquisition methodology and statistical analysis on quantitative performance in label-free proteomics.
J. Dowell   +3 more
semanticscholar   +1 more source

Label-free receptor assays [PDF]

open access: yesDrug Discovery Today: Technologies, 2010
Label-free biosensors offer integrated, kinetic and multi-parametric measures of receptor biology and ligand pharmacology in whole cells. Being highly sensitive and pathway-unbiased, label-free receptor assays can be used to probe the systems cell biology including pleiotropic signaling of receptors, and to characterize the functional selectivity and ...
openaire   +3 more sources

High-resolution Imaging of nanoparticles in wide-field interferometric scattering microscopy [PDF]

open access: yes, 2019
Single particle interferometric scattering microscopy has demonstrated great capability in label-free imaging of sub-wavelength dielectric nanoparticles ...
Avci, Oguzhan   +5 more
core   +1 more source

Metamaterial-based label-free optical biosensing

open access: yesCailiao gongcheng, 2021
Metamaterials have drawn extensive attention for their fine regulation of electromagnetic waves at subwavelength scales. They have abundant electromagnetic modes, and support highly confined and enhanced electromagnetic fields on the surface which are ...
TAO Cheng-dong   +5 more
doaj   +1 more source

Label-free, single molecule detection of cytokines using optical microcavities [PDF]

open access: yes, 2007
Interleukin-2 (IL2) is a cytokine that regulates T-cell growth and is used in cancer therapies. By sensitizing a microcavity sensor surface with anti-IL2 and monitoring the resonant frequency, single molecules of IL2 can be ...
Armani, Andrea M.   +2 more
core   +1 more source

Advancing liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry toward ultra-high-throughput analysis [PDF]

open access: yes, 2020
Label-free high-throughput screening using mass spectrometry has the potential to provide rapid large-scale sample analysis at a speed of more than one sample per second.
Brown, Jeffery   +5 more
core   +1 more source

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

open access: yesJournal of Lipid Research, 2018
In vitro differentiating adipocytes are sensitive to liquid manipulations and have the tendency to float. Assessing adipocyte differentiation using current microscopy techniques involves cell staining and washing, while using flow cytometry involves cell
Vasco Campos   +4 more
doaj   +1 more source

Dynamic acoustic field activated cell separation (DAFACS) [PDF]

open access: yes, 2015
Advances in diagnostics, cell and stem cell technologies drive the development of application-specific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for highthroughput, label-free, high recovery ...
Bernassau, A. L.   +4 more
core   +1 more source

Label-free photoacoustic ophthalmic angiography [PDF]

open access: yesOptics Letters, 2009
We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards.
Hu, Song   +3 more
openaire   +3 more sources

Comparison of a Label-Free Quantitative Proteomic Method Based on Peptide Ion Current Area to the Isotope Coded Affinity Tag Method

open access: yesCancer Informatics, 2008
Recently, several research groups have published methods for the determination of proteomic expression profiling by mass spectrometry without the use of exogenously added stable isotopes or stable isotope dilution theory.
Young Ah Goo   +5 more
doaj   +2 more sources

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