A New Development Paradigm for the Soil-like Utilization of Bulk Industrial Solid Wastes [PDF]
中国工程科学China's metallurgical, coal, and chemical industries annually produce 4 billion tons of bulk industrial solid wastes, posing significant challenges to the green transformation of these industries.
Qingzhu Li +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Pathways for Water-Adaptive Development of Modern Coal Chemical Industry in the Jiziwan Region of the Yellow River Basin [PDF]
中国工程科学The Jiziwan region in the Yellow River basin serves as the strategic core of China's modern coal chemical industry; however, sustainable development of the region is severely constrained by limited water resources.
Yufeng Yang +13 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Systems Engineering for Value-Sustainable Space Exploration: Philosophy, Architecture, and Practice [PDF]
中国工程科学Space exploration activities have progressed into a stage of value-sustainable development. Leading space-faring nations prioritize full lifecycle cost reduction to drive sustainability, enhanced by value-oriented objectives in uncharted frontiers.
Wei Dang +13 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Fault diagnosis system for puffing machine with Bayesian-optimized convolutional neural network and multi-head attention based on multi-source fusion [PDF]
Frontiers of Agricultural Science and EngineeringDue to its high-temperature and high-pressure operating environment, food/feed puffing machines are prone to faults such as cavity blockage and cutter wear.
Daolong HONG +7 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Advancing photocatalytic oxidation process for sustainable treatment of wastewater from livestock production: current breakthroughs and key challenges [PDF]
Frontiers of Agricultural Science and EngineeringWastewater from livestock production is characterized by a complex composition, high pollutant load and the presence of emerging contaminants. These properties lead to critical challenges in conventional treatment processes, including excessive energy ...
Bo SUN +7 more
doaj +1 more source