Results 91 to 100 of about 2,914,902 (352)

Sistem Rekomendasi Hybrid Menggunakan Metode Switching

open access: yesJuTISI (Jurnal Teknik Informatika dan Sistem Informasi)
Perkembangan teknologi memaksa pelaku bisnis untuk memberikan layanan terbaik dengan menjadikan sistem rekomendasi sebagai salah satu solusi untuk menjaga loyalitas konsumen.
Muhammad Rizki, Rianto Rianto
doaj   +1 more source

Bayesian analysis for mixtures of discrete distributions with a non-parametric component [PDF]

open access: yes, 2015
Bayesian finite mixture modelling is a flexible parametric modelling approach for classification and density fitting. Many areas of application require distinguishing a signal from a noise component.
Andrew Harrison   +7 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

High Efficiency Power Amplifier Based on Envelope Elimination and Restoration Technique [PDF]

open access: yes, 2010
Due to complex envelope and phase modulation employed in modern transmitters it is necessary to use power amplifiers that have high linearity. Linear power amplifiers (classes A, B and AB) are commonly used, but they suffer from low efficiency especially
Alou Cervera, Pedro   +9 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Comprehensive Downtime Prediction in Next-Generation Internet

open access: yesInternational Islamic University Malaysia Engineering Journal, 2012
The benchmark for the reliability quality of networks depends mainly on the accuracy and comprehensiveness of the reliability parameters. Downtime prediction of a communication system is crucial for the quality of service (QoS) offered to the end-user ...
W. F. Al-Khateeb, S. Al-Irhayim, and K. A. Al-Khateeb
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

ANALISIS PRODUKSI SUSU SAPI PERAH DI INDONESIA [PDF]

open access: yes, 2023
Cow's milk is large in contributing to meeting the needs of people in developing countries to meet nutritional fulfillment. Cow's milk has increased imports due to the problem of cow disease which cannot meet the needs of the Indonesian people who ...
Khairunnisa, Yanita Melga Fitria
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Adjunctive Use of Calcipotriene/Betamethasone Dipropionate Foam in a Real-World Setting Curtails the Cost of Biologics Without Reducing Efficacy in Psoriasis

open access: yesDermatology and Therapy, 2020
Introduction Although the efficacy of monotherapy with biologics for psoriasis is well established, many patients fail to achieve complete plaque clearance from their initial biologic treatment alone.
Jerry Bagel   +3 more
doaj   +1 more source

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