Results 41 to 50 of about 278,707 (295)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Relabelling Algorithms for Large Dataset Mixture Models [PDF]

open access: yes, 2014
Mixture models are flexible tools in density estimation and classification problems. Bayesian estimation of such models typically relies on sampling from the posterior distribution using Markov chain Monte Carlo.
Fan, Yanan, Zhu, Wanchuang
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

All-Optical Packet Switching and Label Rewriting for Data Packets Beyond 160 Gb/s

open access: yesIEEE Photonics Journal, 2010
In this paper, two different paradigms to realize a scalable all-optical packet switch with label swapping will be reviewed. The two paradigms are based on wavelength routing switch and space routing switch.
Nicola Calabretta   +3 more
doaj   +1 more source

DiffServ Traffic Management with MPLS [PDF]

open access: yes, 2004
La tesi consta di una prima parte teorica, dove vengono analizzate nell’ordine: i) Differentiated Services; ii) MultiPotocol Label Switching; iii) Traffic Engineering.
Lepera, Pasquale
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of CYP2C19 status on platelet reactivity in Taiwanese acute coronary syndrome patients switching to prasugrel from clopidogrel: Switch Study

open access: yesJournal of the Formosan Medical Association, 2022
Background/Purpose: Pharmacogenetics is a potential driver of the “East Asian paradox,” in which East Asian acute coronary syndrome (ACS) patients receiving dual antiplatelet therapy (DAPT) with clopidogrel following percutaneous coronary intervention ...
Feng-Yu Kuo   +15 more
doaj   +1 more source

Motivation crowding in real consumption decisions: Who is messing with my groceries? [PDF]

open access: yes, 2014
We present evidence of crowding out of intrinsic motivation in real purchasing decisions from a field experiment in a large supermarket chain. We compare three instruments, a label, a subsidy and a neutral price change, in their ability to induce ...
Andreoni   +38 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Optical label switching

open access: yesOptical Fiber Communication Conference and International Conference on Quantum Information, 2001
Summary form only given. The design and implementation of a optical label switched router for packet switched WDM networks will be presented. The algorithms of generating optical labels, look-up tables, routing protocols, and a scaleable network architecture similar to IP/MPLS in optical domain will also be discussed.
openaire   +2 more sources

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