Results 61 to 70 of about 2,887,200 (357)

Switching of Photocatalytic Tyrosine/Histidine Labeling and Application to Photocatalytic Proximity Labeling

International Journal of Molecular Sciences, 2022
Weak and transient protein interactions are involved in dynamic biological responses and are an important research subject; however, methods to elucidate such interactions are lacking. Proximity labeling is a promising technique for labeling transient ligand–binding proteins and protein–protein interaction partners of analytes via an irreversible ...
Keita Nakane, Haruto Nagasawa, Chizu Fujimura, Eri Koyanagi, Shusuke Tomoshige, Minoru Ishikawa, Shinichi Sato   +6 more
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

All-Optical Packet Switching and Label Rewriting for Data Packets Beyond 160 Gb/s

IEEE Photonics Journal, 2010
In this paper, two different paradigms to realize a scalable all-optical packet switch with label swapping will be reviewed. The two paradigms are based on wavelength routing switch and space routing switch.
Nicola Calabretta, Hyun-Do Jung, Eduward Tangdiongga, Harmen Dorren   +3 more
doaj   +1 more source

DiffServ Traffic Management with MPLS [PDF]

, 2004
La tesi consta di una prima parte teorica, dove vengono analizzate nell’ordine: i) Differentiated Services; ii) MultiPotocol Label Switching; iii) Traffic Engineering.
Lepera, Pasquale
core  

Efficacy and Safety of Switching from Innovator Rituximab to Biosimilar CT-P10 Compared with Continued Treatment with CT-P10: Results of a 56-Week Open-Label Study in Patients with Rheumatoid Arthritis

BioDrugs, 2017
CT-P10 is a biosimilar candidate of innovator rituximab (RTX) that demonstrated a comparable clinical profile to RTX in a phase I randomized controlled trial (RCT) in rheumatoid arthritis (RA) (ClinicalTrials.gov identifier: NCT01534884). This open-label
W. Park, C. Suh, S. Shim, F. F. C. Molina, S. Jeka, F. Medina-Rodriguez, P. Hrycaj, P. Wiland, Eun Young Lee, P. Shesternya, V. Kovalenko, L. Myasoutova, M. Stanislav, S. Radominski, M. Lim, J. Choe, Sang Joon Lee, S. Y. Lee, Sung Hwan Kim, D. Yoo   +19 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

A label-free thrombin photoelectrochemical aptasensor based on structure-switching in G-quadruplexes

Biosensors and Bioelectronics: X, 2022
In this work, an Au/GaN photoelectrode was prepared by sputtering a 30.0-nm–thick gold film on an n-type gallium nitride (GaN) surface. Guanine (G) was used as a hole trap in photoinduced charge separation due to its lowest oxidation potential and ...
Xiujun Rong, Huilan Zhang, Weicheng Cai, Fang Luo, Cuiying Lin, Bin Qiu, Zhenyu Lin, Jian Wang, Zhou Jiang, Hui Huang   +9 more
doaj   +1 more source

Evaluation of Biomarkers of Exposure in Smokers Switching to a Carbon-Heated Tobacco Product: A Controlled, Randomized, Open-Label 5-Day Exposure Study

Nicotine & Tobacco Research, 2016
Introduction: Tobacco harm reduction aims to provide reduced risk alternatives to adult smokers who would otherwise continue smoking combustible cigarettes (CCs).
F. Lüdicke, C. Haziza, R. Weitkunat, J. Magnette   +3 more
semanticscholar   +1 more source

Multifunctional Switch Based on Spin-Labeled Gold Nanoparticles

Nano Letters, 2022
The fabrication of multifunctional switches is a fundamental step in the development of nanometer-scale molecular spintronic devices. The anchoring of active organic radicals on gold nanoparticles (AuNPs) surface is little studied and the realization of AuNPs-based switches remains extremely challenging.
Vega Lloveras, Pilar Elías-Rodríguez, Luca Bursi, Ehsan Shirdel, Alejandro R. Goñi, Arrigo Calzolari, José Vidal-Gancedo   +6 more
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source