Results 61 to 70 of about 330,705 (346)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

All-Optical Packet Switching and Label Rewriting for Data Packets Beyond 160 Gb/s

IEEE Photonics Journal, 2010
In this paper, two different paradigms to realize a scalable all-optical packet switch with label swapping will be reviewed. The two paradigms are based on wavelength routing switch and space routing switch.
Nicola Calabretta, Hyun-Do Jung, Eduward Tangdiongga, Harmen Dorren   +3 more
doaj   +1 more source

Switching of Photocatalytic Tyrosine/Histidine Labeling and Application to Photocatalytic Proximity Labeling

International Journal of Molecular Sciences, 2022
Weak and transient protein interactions are involved in dynamic biological responses and are an important research subject; however, methods to elucidate such interactions are lacking. Proximity labeling is a promising technique for labeling transient ligand–binding proteins and protein–protein interaction partners of analytes via an irreversible ...
Keita Nakane, Haruto Nagasawa, Chizu Fujimura, Eri Koyanagi, Shusuke Tomoshige, Minoru Ishikawa, Shinichi Sato   +6 more
openaire   +2 more sources

SCM optical label switching scheme in a WDM packet transmitter employing a switching SG-DBR laser [PDF]

, 2006
We demonstrate an SCM optical label switching scheme with spectral efficiency of 0.4bit/s/Hz and a spectral density figure of merit of 1. We then employ this scheme in a WDM transmitter subsystem and we investigate the detrimental effects that switching ...
Barry, Liam P., Connolly, Eoin M., Cotter, D., Ellis, A.D., Kaszubowska-Anandarajah, Aleksandra, Mishra, A.K., Smyth, Frank   +6 more
core   +1 more source

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

Molecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler, Emily Brieger, Tom Brandstätter, Elisa Hörterer, Ulrich Wilk, Jana Pöhmerer, Anna Jötten, Philipp Paulitschke, Chase P. Broedersz, Stefan Zahler, Joachim O. Rädler, Ernst Wagner, Andreas Roidl   +12 more
wiley   +1 more source

Switch Point biased Self-Training: Re-purposing Pretrained Models for Code-Switching [PDF]

arXiv, 2021
Code-switching (CS), a ubiquitous phenomenon due to the ease of communication it offers in multilingual communities still remains an understudied problem in language processing. The primary reasons behind this are: (1) minimal efforts in leveraging large pretrained multilingual models, and (2) the lack of annotated data.
arxiv  

160 Gb/s optical packet switch module employing SOI integrated label extractor [PDF]

, 2013
We demonstrate a full functional 1×N optical packet switch employing a Silicon-on-Insulator integrated label extractor combined with a FPGA-based controller.
Calabretta, N, De Heyn, Peter, Di Lucente, S, Dorren, HJS, Luo, J, Van Thourhout, Dries   +5 more
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Improving Low Resource Code-switched ASR using Augmented Code-switched TTS [PDF]

arXiv, 2020
Building Automatic Speech Recognition (ASR) systems for code-switched speech has recently gained renewed attention due to the widespread use of speech technologies in multilingual communities worldwide. End-to-end ASR systems are a natural modeling choice due to their ease of use and superior performance in monolingual settings.
arxiv  

Progressive Sentiment Analysis for Code-Switched Text Data [PDF]

arXiv, 2022
Multilingual transformer language models have recently attracted much attention from researchers and are used in cross-lingual transfer learning for many NLP tasks such as text classification and named entity recognition. However, similar methods for transfer learning from monolingual text to code-switched text have not been extensively explored mainly
arxiv