Results 81 to 90 of about 674,208 (280)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
List (d,1)-total labelling of graphs embedded in surfaces [PDF]
, 2011 The (d,1)-total labelling of graphs was introduced by Havet and Yu. In this paper, we consider the list version of (d,1)-total labelling of graphs. Let G be a graph embedded in a surface with Euler characteristic $\epsilon$ whose maximum degree $\Delta(G)
Liu, Guizhen, Yu, Yong, Zhang, Xin
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Oilseeds and fats, crops and lipids, 2016 The present article is aimed at presenting various types of certification standards which are presently – or could be – applied to the production of palm oil. Doing so, it provides an overview of the existing mechanisms under way both at the European and
Rival Alain, Montet Didier, Pioch Daniel
doaj +1 more source
„Mut des Wortes“ – „Mut der Tat“?
Österreichische Zeitschrift für Geschichtswissenschaften, 2010 The cultural landscape of the capital of the first Czechoslovak Republic was marked by many different spaces of communication which were closely linked to certain communities (formed on the basis of national / ‘ethnic’ association).
Stefan Benedik
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Wet gum labelling of wine bottles [PDF]
, 1996 It is shown that bubbling on wine bottle labels is due to absorption of water from the glue, with subsequent hygroscopic expansion. Contrary to popular belief, most of the glue's water must be lost to the atmosphere rather than to the paper.
Broadbridge, P., Chan, D.
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
[2H26]-1-epi-Cubenol, a completely deuterated natural product from Streptomyces griseus
Beilstein Journal of Organic Chemistry, 2013 During growth on fully deuterated medium the volatile terpene [2H26]-1-epi-cubenol was released by the actinomycete Streptomyces griseus. This compound represents the first completely deuterated terpene obtained by fermentation.
Christian A. Citron, Jeroen S. Dickschat
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