Results 51 to 60 of about 14,351 (208)

Comparing the Molecular Pharmacological Properties of Existing β‐Blockers to Determine the Theoretically Most “Ideal” Anti‐Cancer β‐Blocker

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Jillian G. Baker
wiley   +1 more source

Comparing the Effect of Labetalol versus Morphine on Controlling Blood Pressure and Pulse Rate During Emergence from Anesthesia after Craniotomy

Advanced Biomedical Research, 2017
Background: Emergence from anesthesia is associated with sympathetic stimulation, increase in pulse and blood pressure. There are different methods, but the most appropriate method should be selected regarding the differences in nationalities. This study
Mohammadali Attari, Fatemeh Tayyari, Nafiseh Narimani   +2 more
doaj   +1 more source

A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)

Clinical Endocrinology, Volume 104, Issue 2, Page 113-122, February 2026.
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea, Frédérique Lefrançois, Matthieu St‐Jean, Anne‐Marie Côté, Marie‐Ève Roy‐Lacroix, Mandy Malick, Pierre‐Luc Mallet, Nadine Sauvé   +7 more
wiley   +1 more source

Labetalol Pretreatment Reduces Blood Pressure Instability During Surgical Resection of Pheochromocytoma

Journal of the Formosan Medical Association, 2006
To evaluate the effect of pretreatment with the mixed alpha- and beta-adrenergic blocker, labetalol, on blood pressure instability during surgical resection of pheochromocytoma. Methods: Blood pressure stability and surgical results were compared between
Peter Chi-Ho Chung, Yuet-Tong Ng, Jing-Ru Hsieh, Min-Wen Yang, Allen Hon-Lun Li   +4 more
doaj   +1 more source

Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials

Hypertension in Pregnancy, 2022
Objectives This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy.
Hui-Zhen Wu, Yuan Cheng, Ding Yu, Ji-Bin Li, Yun-Fa Jiang, Zhong-Ning Zhu   +5 more
doaj   +1 more source

Concurrent Reversible Cerebral Vasoconstriction Syndrome and Bilateral Vertebral Artery Dissection in the Postpartum Period: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Reports of postpartum women with concurrent reversible cerebral vasoconstriction syndrome (RCVS) and bilateral vertebral artery dissection (VAD) are rare. Guidelines on the management of future pregnancies in these patients are also limited.
Rong Jin, Huiliang Melissa Tang, Shavi Fernando   +2 more
wiley   +1 more source

Adrenal pheochromocytoma incidentally discovered in a patient with parkinsonism [PDF]

, 2015
To evaluate the diagnostic route of pheochromocytoma (PHEO) in a patient under dopaminergic treatment. A 70-year-old man with Parkinsonism and under treatment with levodopa and carbidopa came to our observation for evaluation of arterial hypertension and
Claudio Letizia, Concistrè Antonio, Giuseppe De Vincentis, Iannucci Gino, Lucia Piernatale, Luigi Petramala, Marinelli Cristiano, Zinnamosca Laura   +7 more
core   +1 more source

A Novel Tertiary Carbamate Prodrug Strategy to Overcome Metabolic Barriers in Oral Ketamine Delivery

ChemMedChem, Volume 21, Issue 2, January 2026.
This study describes the development of an orally optimized ketamine prodrug designed to improve pharmacokinetic properties, extend therapeutic efficacy, and minimize adverse effects and abuse liability. Ketamine, a rapid‐acting N‐methyl‐D‐aspartate (NMDA) receptor antagonist, has therapeutic potential beyond anesthesia, including treatment‐resistant ...
Juulia Järvinen, Santosh Kumar Adla, Janne Tampio, Aaro Jalkanen, Kenneth B. Sloan, Kristiina M. Huttunen, Jarkko Rautio   +6 more
wiley   +1 more source

Comparison of Oral Preoperative Clonidine with Infusion of Intraoperative Labetalol on Bleeding during Tympanoplasty Surgery [PDF]

Iranian Journal of Otorhinolaryngology
Introduction: Surgical bleeding is one of the most critical complications in various surgical procedures. In middle ear surgery, managing bleeding is a significant challenge for anesthesiologists because even minor bleeding can obstruct the surgeon's ...
Mohamad Reza Afzalzadeh, Mostafa Mahdavi, Saleheh Asghari, Maryam Emadzadeh   +3 more
doaj   +1 more source

A Rational Approach to Pharmacotherapy in Pregnancy

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen, Kevin Watt, Ahizechukwu C. Eke   +2 more
wiley   +1 more source