Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Preventing burnout: Community health worker perspectives on professional development and emotional labor overload - A qualitative descriptive study. [PDF]
Achore M, Hackett M, Ramirez T.
europepmc +1 more source
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Between Syndemics and Structural Exploitation: Health Barriers of Migrant Agricultural Workers. [PDF]
Kurlander Y +5 more
europepmc +1 more source
A Supramolecular Reversible and Anisotropic Conductive Adhesive for Flexible Electronics
Supramolecular network‐based nanocomposites are developed as a stretchable conductive adhesive for flexible electronics. It's as convenient as traditional solders and constructs anisotropic conductive and robust stretchable connections among diverse soft/rigid materials.
Tongtong Li +8 more
wiley +1 more source
Research on reasonable length of steeply dipping coal seam working face based on the fuzzy comprehensive evaluation method. [PDF]
Zhang H, Guo Z, Ma F, Liu Y.
europepmc +1 more source
Self‐Adhesive Conductive Elastomers for Gel‐Free Biopotential Recording
σPOMaC, a self‐adhesive conductive citrate elastomer incorporating PEDOT:PSS and DBSA, enables gel‐free biopotential electrodes with stable conductivity and intrinsic skin adhesion. The composite exhibits low resistivity (∼ 0.02 Ω·cm), robust electrical performance during repeated use, and reliable on‐body ECG acquisition comparable to Ag/AgCl ...
Kirstie M. K. Queener +7 more
wiley +1 more source
Determinants of blood lead and cadmium levels in sanitary landfill workers: a cross-sectional study in Greece. [PDF]
Kareli A +5 more
europepmc +1 more source

