Results 131 to 140 of about 31,744 (234)

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

Journal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira, Rogerio Salvini, Eloisa Dutra Caldas   +2 more
wiley   +1 more source

Laboratórios e interiores. 13.

, 1980
Laboratórios e interiores ...
Romualdo Ruico Resquim Sicco
core  

Exposure–Recovery Approach for Hepatic Toxicity Analysis of Pyrethroid Lambda‐Cyhalothrin: Histopathological, Histochemical, and Biochemical Responses in Oreochromis niloticus

Journal of Applied Toxicology, EarlyView.
ABSTRACT Lambda‐cyhalothrin is a synthetic pyrethroid insecticide widely used in agriculture, but its potential to contaminate aquatic ecosystems and exert high toxicity on fish at low concentrations raises ecotoxicological concerns. While standard histopathological and biochemical assessments are common, the novel integration of pigment‐based ...
Carlos Eurico Fernandes, André Luiz do Nascimento Silva, Tiago Venancio da Silva, Karine Nathiele Nogueira Farias, Sabrina Fuzer Gonçalves, Brenda de Oliveira Martins, Maria Eduarda Corona Garcia, Lilian Franco‐Belussi   +7 more
wiley   +1 more source

Exposure‐Based Toxicological Evaluation of Lead and Elemental Impurities in Encapsulated Green Tea Dietary Supplements Under a Regulatory Framework

Journal of Applied Toxicology, EarlyView.
ABSTRACT The consumption of green tea (Camellia sinensis (L.) Kuntze) in the form of encapsulated dietary supplements has increased substantially in recent years; however, data supporting toxicological risk assessment of inorganic contaminants in these products remain limited.
Amanda da Silva Chaves, Lisia Maria Gobbo dos Santos, Beatriz Scaramelo, Júlia Maria Peixoto Loureiro, Fabio Coelho Amendoeira, Silvana do Couto Jacob, Fausto Klabund Ferraris   +6 more
wiley   +1 more source

ESTUDO DE ALELOS MUTADOS EM GENE QUE PARTICIPA DA PRODUÇÃO E SECREÇÃO DE LIPOPROTEÍNAS EM PORTADORES CRÔNICOS DO VÍRUS DA HEPATITE C

Brazilian Journal of Infectious Diseases, 2021
Thamiris Vaz Gago Prata, Fátima Mitiko Tengan, Bianca Peixoto Dantas, Arielle Karen da Silva Nunes, Caroline Manchiero, Mariana Cavalheiro Magri   +5 more
doaj   +1 more source

Laboratórios e interiores. 17.

, 1980
Laboratórios e interiores ...
Romualdo Ruico Resquim Sicco
core  

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat

Journal of Clinical Laboratory Analysis, EarlyView.
Distal 1q43q44 deletions lead to a consistent neurodevelopmental phenotype characterized by microcephaly, corpus callosum abnormalities, and developmental delay. Despite differences in genomic architecture, overlapping deletions affecting dosage‐sensitive genes such as AKT3, HNRNPU, and ZBTB18 define the core phenotype.
Ma. Guadalupe Domínguez‐Quezada, Horacio Rivera, Luis E. Figuera, Patricio Barros‐Núñez, José Luis Castrillo, Carlos Córdova‐Fletes, Thania Alejandra Aguayo‐Orozco   +6 more
wiley   +1 more source

Quality indicators for the management of clinical simulation centers and laboratories: a scoping review. [PDF]

Rev Lat Am Enfermagem
Santos ISN, Souza CJ, Hipolito RL, Oliveira MF, Ribeiro CB, Brites ADS.   +5 more
europepmc   +1 more source

Performance Evaluation of the VISITECT CD4 Lateral Flow Point‐Of‐Care Assay for Identifying Advanced HIV Disease

Journal of Clinical Laboratory Analysis, EarlyView.
The VISITECT CD4 lateral flow assay (LFA) was evaluated for identifying advanced HIV disease (CD4 ≤ 200 cells/μL) during routine programmatic implementation in Argentina. The assay showed 100% sensitivity, while specificity improved after observer training, reflecting reduced reader‐dependent variability.
Mariana Andreani, Claudia E. Frola, Liliana Guelfand, Fabiana C. Chaile, José Barletta, María J. Rolón, Mariana Erbin, Juan L. Rodriguez‐Tudela   +7 more
wiley   +1 more source