XIX.—Notes from the Gatty Marine Laboratory, St. Andrews.—No. XL [PDF]
, 1917 M'Intosh
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
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The Historical Development and Relative Value of Laboratory and Clinical Methods of Diagnosis [PDF]
, 1907 Richard C. Cabot
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Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
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Minor studies from the psychological laboratory of the Wellesley College: The perception of the distance of sound. [PDF]
, 1909 Daniel Starch, Anne L. Crawford
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Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
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Some Laboratory Applications of the Low Friction Properties of the Dry Hypodermic Syringe [PDF]
, 1947 H. F. Brubach
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
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Qualitative Chemical Analysis. A Laboratory Guide . By W. W. Scott, A.M., chief chemist, Baldwin Locomotive works, formerly Professor of Chemistry, Morningside College, New York. D. Van Nostrand Co. 1910. $1.50 net; A Course in Qualitative Chemical Analysis . By Charles Baskerville, Ph.D., F.C.S., Professor in the Department of Chemistry of the College of the City of New York, and L. J. Curtman, Ph.D., Instructor in the Department of Chemistry of the College of the City of New … [PDF]
, 1912 Otto Glaser
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