Results 181 to 190 of about 5,416,068 (411)

13.8 kV, 5 MVA Medium Voltage Test Facility: Design, Implementation and Lessons Learned

IEEE Open Journal of Power Electronics
Hands-on, testing laboratories are fundamental to technical learning environments in universities. The need for modern equipment in these labs to support industry research and testing is often cost prohibitive and students and professors rely on a random
Brandon M. Grainger, Daniel J. Carnovale
doaj   +1 more source

Las actividades de laboratorio en Física: un cambio en la estructura a favor del conocimiento científico [PDF]

arXiv
In this article we argue how the use of structured laboratory guides are pedagogically inadequate for meaningful learning. Subsequently, an approach to laboratory activities in accordance with scientific work and the constructivist vision of learning is described, exemplifying how this approach can be applied to restructure a usual laboratory practice.
arxiv  

Pilot-Scale Laboratory Instruction for ChE: the specific case of the Pilot-unit leading group [PDF]

, 2010
This paper presents an original approach for Chemical Engineering laboratory teaching that is currently applied at INP-ENSIACET (France). This approach, referred to as "pilot-unit leading group" is based on a partial management of the laboratories by the
Billet, Anne-Marie, Camy, Séverine, Coufort, Carole   +2 more
core  

The Teaching Botanist. W. F. GanongBotany for High Schools. George F. AtkinsonLaboratory Botany. Willard N. Clute [PDF]

, 1911
W. L. Eikenberry
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The scourge of antimicrobial resistance: Containing a global crisis

African Journal of Laboratory Medicine
No abstract available.
Rajiv T. Erasmus, Chikwelu L. Obi, Sajini Souda   +2 more
doaj   +1 more source

Virtual laboratories for education in science, technology, and engineering: A review

Comput. Educ., 2016
V. Potkonjak, M. Gardner, V. Callaghan, Pasi Mattila, Christian Gütl, V. Petrović, Kosta M. Jovanovic   +6 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source