Results 11 to 20 of about 1,631,615 (310)

Scientists and the 3Rs: attitudes to animal use in biomedical research and the effect of mandatory training in laboratory animal science [PDF]

, 2014
The 3Rs principle of replacement, reduction, and refinement has increasingly been endorsed by legislators and regulatory bodies as the best approach to tackle the ethical dilemma presented by animal experimentation in which the potential benefits for ...
IAS Olsson, Olsson, IAS, NH Franco, Franco, Nuno H., Franco, NH, Olsson, I Anna S   +5 more
core   +1 more source

The establishment of a recombinase polymerase amplification technique for the detection of mouse poxvirus

BMC Veterinary Research, 2023
Background Ectromelia virus (ECTV) is the causative agent of mousepox in mice. In the past century, ECTV was a serious threat to laboratory mouse colonies worldwide.
Yuexiao Lian, Mengdi Zhang, Yujun Zhu, Miaoli Wu, Bihong Huang, Li Xiao, Kehang Shi, Peide Li, Feng Cong, Huanan Wang   +9 more
doaj   +1 more source

Survey of the quality of experimental design, statistical analysis and reporting of research using animals [PDF]

, 2009
For scientific, ethical and economic reasons, experiments involving animals should be appropriately designed, correctly analysed and transparently reported.
Festing, Michael F. W., Festing, MF, Douglas G Altman, Parsons, Nicholas R., Altman, D.G, Ed Kadyszewski, Nick Parsons, Kilkenny Carol, Kilkenny, C, Fry, D, Derek Fry, Parsons Nick, Fry Derek, Altman, DG, Altman, Douglas G., Cuthill, IC, Cuthill Innes C., Festing, M.F.W, Kadyszewski, Ed, Hutton, Jane, Fry, Derek, Kadyszewski, E, Carol Kilkenny, Jane Hutton, Innes C Cuthill, Festing Michael F. W., Cuthill, Innes C., Altman Douglas G., Hutton, J, Kadyszewski Ed, Parsons, N, Michael F W Festing, Kilkenny, Carol, Hutton Jane   +33 more
core   +1 more source

Development and evaluation of a broadly reactive reverse transcription recombinase polymerase amplification assay for rapid detection of murine norovirus

BMC Veterinary Research, 2018
Background Murine norovirus (MNV) is recognized as the most prevalent viral pathogen in captive mouse colonies. The rapid detection assay for MNV would be a useful tool for monitoring and preventing MNV infection.
Lei Ma, Fanwen Zeng, Feng Cong, Bihong Huang, Yujun Zhu, Miaoli Wu, Fengjiao Xu, Wen Yuan, Ren Huang, Pengju Guo   +9 more
doaj   +1 more source

Establishment of Hematological and Serum Biochemical Parameters in 4,834 Healthy Cynomolgus Monkeys (Macaca fascicularis)

BIO Integration, 2022
Background: In China and other countries, cynomolgus monkeys are commonly used experimental animal models in biomedical research. Reference hematologic and biochemical parameters must be established to evaluate healthy cynomolgus monkeys and investigate ...
Xueying Ling, Ting Luo, Qingyu Huang, Ying He, Longbao Lv, Yun Wang, Ronghua Ma, Jiewen Chen, Jicun He, Jinrong Zhang, Hongyu Lu, Jian He, Danrong Lin, Siyu Chen, Taiqi Liu, Yangqing Guo, Zhuhong Liu, Jiaqi Feng, Yudan Mao, Zhiying Chen, Ren Huang, Wen De Li   +21 more
doaj   +1 more source

A multiplex xTAG assay for the simultaneous detection of five chicken immunosuppressive viruses

BMC Veterinary Research, 2018
Background Chicken anemia virus (CAV), avian reovirus (ARV), infectious bursal disease virus (IBDV), Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) all cause immunosuppressive disease in birds through vertical or horizontal ...
Feng Cong, Yujun Zhu, Jing Wang, Yuexiao Lian, Xiangnan Liu, Li Xiao, Ren Huang, Yu Zhang, Meili Chen, Pengju Guo   +9 more
doaj   +1 more source

Laboratory Animal Allergens [PDF]

ILAR Journal, 2001
Allergic sensitivity to laboratory animals can pose a significant occupational hazard to anyone with regular animal contact. Reactions to mice and rats are most common although all furred animals produce allergens that can lead to sensitization and disease.
openaire   +2 more sources

The rabbit gingival tissue response to retraction liquids and tetrahydrozoline [PDF]

Vojnosanitetski Pregled, 2014
Backround/Aim. Retraction agents for temporary vertical and lateral suppression of gingival tissue as well as bleeding control and fluid flow in the gingival sulcus are expected to have maximal efficiency without irreversible damage of local ...
Kostić Ivan, Mihailović Dragan, Najman Stevo, Stojanović Sanja, Kostić Milena   +4 more
doaj   +1 more source

Development of a sensitive and specific xMAP assay for detection of antibodies against infectious laryngotracheitis and bronchitis viruses

Virology Journal, 2018
Background A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of antibodies titers after vaccination.
Huanan Wang, Feng Cong, Jianchi Guan, Li Xiao, Yujun Zhu, Yuexiao Lian, Ren Huang, Meili Chen, Pengju Guo   +8 more
doaj   +1 more source

Use of animals in dental research: Trends and ethical reflections

, 2022
This study aimed to survey and analyze the profile of experimental dental research in animals, verifying its trends. We evaluated studies developed with the use of animals in vivo, published in 10 dental journals with high impact factors, from 2015 to ...
Fernandes, Clemente Maia S [UNESP], Lopes, Camila Soares [UNESP], Serra, Mônica da Costa [UNESP], Barbosa, Aline Cristina S [UNESP]   +3 more
core   +1 more source