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The assessment of researchers' competence in experimental procedures with laboratory animals: A three-step methodology to develop a global rating scale [PDF]
To conduct animal experiments, researchers must be competent to handle and perform interventions on living animals in compliance with regulations. Laboratory animal science training programs and licensing bodies therefore need to be able to reliably ...
Costa, MJ +3 more
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Amphibians as Laboratory Animals [PDF]
Scientists Center for Animal Welfare (Available from SCAW, Golden Triangle Building One, 7833 Walker Drive, Suite 340, Greenbelt, MD 20770. Tel: 301/345-3500; Fax: 301/345-3503). Scott WB, Crossman EJ. 1973. Freshwater Fish of Canada. Fisheries Research Board of Canada, Bulletin 184. Snodgrass MJ, Burke JD, Meetz GD. 1976.
openaire +2 more sources
Background Porcine circovirus type 3 (PCV3) is an emerging circovirus species, that has been reported in major pig-raising countries including the United States, China, South Korea, Brazil, Spain, and Poland.
Huanan Wang +13 more
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Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer in the clinic. Further discovery of novel drugs or therapeutic protocols that enhance efficacy requires reliable animal models that recapitulate human immune responses to ICI
Ikumi Katano +9 more
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IntroductionPorcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most threatening pathogens of swine. The nucleocapsid (N) protein is the major structural protein of the virus and has been used as a PRRSV diagnostic antigen due ...
Yuening Cheng +6 more
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Isolation and characterization of Bordetella pseudohinzii in mice in China
We report on the first detection and isolation of B. pseudohinzii (Bordetella pseudohinzii) in laboratory mice in China. Forty‐one B. pseudohinzii strains were isolated from 3094 mice in 33 different laboratory animal facilities in southern China.
Lei Ma +8 more
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Prediction of Compound Synthesis Accessibility Based on Reaction Knowledge Graph
With the increasing application of deep-learning-based generative models for de novo molecule design, the quantitative estimation of molecular synthetic accessibility (SA) has become a crucial factor for prioritizing the structures generated from ...
Baiqing Li, Hongming Chen
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Approximately one third of laboratory animal workers have occupational allergy to animal danders, and a third of these have symptomatic asthma. Sensitization generally occurs with the first 3 years of employment, and risk factors include atopic background, as well as job description as it relates to the intensity of exposure.
R K, Bush, R A, Wood, P A, Eggleston
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Tumor necrosis factor alpha (TNFα) plays a key role in the pathogenesis of rheumatoid arthritis (RA). Blockade of TNFα by monoclonal antibody has been widely used for the therapy of RA since the 1990s; however, its mechanism of efficacy, and potential ...
Ge Li +6 more
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Alternatives to Carbon Dioxide—Taking Responsibility for Humanely Ending the Life of Animals
Carbon dioxide (CO2) is commonly used to kill rodents. However, a large body of research has now established that CO2 is aversive to them. A multidisciplinary symposium organized by the Swiss Federal Food Safety and Veterinary Office discussed the ...
Shannon Axiak Flammer +8 more
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