Results 101 to 110 of about 654,754 (303)

Evaluation of Broth Disk Elution Method to Determine Colistin Resistance in Klebsiella pneumoniae and Escherichia coli Strains

, 2023
© Copyright.Background: The reference broth microdilution (rBMD) method for the determination of colistin resistance is very laborious and time consuming, and many manual errors can occur.
Nilgun Kansak, Riza Adaleti, Sebahat Aksaray, Neslihan Arici, Uzunoner, Yasemin, Kansak, Nilgun, Nevriye Gonullu, GÖNÜLLÜ, NEVRİYE, Arici, Neslihan, Adaleti, Riza, Aksaray, Sebahat, Yasemin Uzunoner   +11 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Types and frequency of laboratory errors in Sawanpracharak hospital, Nakornsawan province: One year after laboratory accreditation

Journal of Associated Medical Sciences, 2010
Since  laboratory  tests  provide  essential  information  for  physicians  to  make  medical  decisions  for diagnosis, treatment and monitoring of the patient’s condition, we evaluated the types and frequency of errors in our  in-patient  department ...
Pakasit Pratoomtone
doaj  

Study of pre-analytical errors in clinical biochemistry laboratory in Dhiraj General hospital, Piparia

, 2022
Introduction: Pre-analytical errors is the major source of mistakes in laboratory diagnostics. It includes from order of test by physician to sample is ready for analysis.
Devanshi Gosai, Vasava, Smita, Smita Vasava, Sadaria, Roshni, Roshni Sadaria, Gosai, Devanshi   +5 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Global serum glycoform profiling for the investigation of dystroglycanopathies & Congenital Disorders of Glycosylation

Molecular Genetics and Metabolism Reports, 2016
The Congenital Disorders of Glycosylation (CDG) are an expanding group of genetic disorders which encompass a spectrum of glycosylation defects of protein and lipids, including N- & O-linked defects and among the latter are the muscular ...
Wendy E. Heywood, Emily Bliss, Philippa Mills, Jale Yuzugulen, Gabriela Carreno, Peter T. Clayton, Francesco Muntoni, Viki C. Worthington, Silvia Torelli, Neil J. Sebire, Kevin Mills, Stephanie Grunewald   +11 more
doaj   +1 more source

Errors of clinical diagnostics laboratory and their management

, 2010
Aim of the study: Evaluate clinical diagnostics laboratory errors and their management possibilities. Study methodology: Laboratory X error registry study performed (2007 – 2009 year).
Keliuotienė, Rasma
core  

Clinical biochemistry laboratory rejection rates due to various types of preanalytical errors

, 2014
Introduction: Preanalytical errors, along the process from the beginning of test requests to the admissions of the specimens to the laboratory, cause the rejection of samples.
Cuhadar, Serap, Ozkan, Asuman, Saliha Aksun, Gulcan Saglam, Saglam, Gulcan, Sutcu, Recep, Unal, Hulya, Hulya Unal, Leyla Demir, Arslan, Banu, Banu Arslan, Recep Sutcu, Aksun, Saliha, Serap Cuhadar, Atay, Aysenur, Aysenur Atay, Asuman Ozkan, Demir, Leyla   +17 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source