Results 121 to 130 of about 1,573,361 (315)

Decreased risk of non-influenza respiratory infection after influenza B virus infection in children [PDF]

Previous studies suggest influenza virus infection may provide temporary nonspecific immunity and hence lower the risk of non-influenza respiratory virus infection. In a randomized controlled trial of influenza vaccination, 1330 children were followed-up
Fang, Vicky J., Chu, Daniel K.W., Lau, Eric H.Y., Ip, Dennis K.M., Cauchemez, Simon, Du, Richael Q.R., Tsang, Tim K., Leung, Gabriel M., Chan, Kwok Hung, Cowling, Benjamin J., Peiris, J. S. Malik.   +10 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Synergistic Therapeutic Effects and Immunoregulatory Mechanism of Maxing Shigan Decoction Combined with Sijunzi Decoction on Viral Pneumonia in Mice

Canadian Journal of Infectious Diseases and Medical Microbiology
Influenza is defined in traditional Chinese medicine (TCM) as an epidemic febrile illness and is usually treated with herbal compound formulas under the guidance of the “Qu Xie and Fu Zheng” theories.
Huimin Huang, Huanhua Yang, Zurong Zhang, Yunlong Song, Li Li, Ke Li, Junjie Zhang, Xiaoyu Qi, Ying Wu   +8 more
doaj   +1 more source

TroA of Streptococcus suis is required for manganese acquisition and full virulence

, 2011
Streptococcus suis causes infections in pigs and occasionally in humans resulting in 23 manifestations as meningitis, sepsis, arthritis and septic shock. For survival within the 24 host, S. suis requires numerous nutrients including trace metals.
Smith, H.E., Rebel, M.J., Wichers Schreur, P.J., Rebel, J.M.J., van Putten, J.P.M., Jos P. M. van Putten, Johanna M. J. Rebel, Mari A. Smits, Paul J. Wichgers Schreur, Smits, M.A., Hilde E. Smith, Wichgers Schreur, P.J., Putten, J.P.M., van   +12 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Survival of Theileria parva in its nymphal tick vector Rhipicephalus appendiculatus under laboratory and quasi natural conditions [PDF]

, 2003
Groups of nymphal Rhipicephalus appendiculatus Muguga, having a mean of 1 or 9 Theileria parva Muguga-infected salivary gland acini per tick, were kept under quasi-natural conditions at an altitude of 1950 m or 20°C at a relative humidity of 85% in the ...
Young, A. S., Medley, Graham, Ochanda, Horace   +2 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells

Journal of Experimental & Clinical Cancer Research, 2016
Background Interleukin-7 receptor (IL-7R) is involved in the abnormal function of solid tumors, but the role and regulatory mechanisms of IL-7R in HBV-related hepatocellular carcinoma (HCC) are still unclear. Methods Gene and protein expression levels of
Fanyun Kong, Wei Hu, Kai Zhou, Xiao Wei, Yanbo Kou, Hongjuan You, Kuiyang Zheng, Renxian Tang   +7 more
doaj   +1 more source

Laboratory safety and laboratory-acquired infection control.

Laboratory safety and laboratory-acquired infection control.
Malkit Singh (18283796), Gaurav Chhabra (18283790), Sanjeev Kumar (279609), Kaptan Singh Sehrawat (18283793)   +3 more
core   +1 more source

Urinary porphyrin excretion in hepatitis C infection [PDF]

, 1999
A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism.
Jacob, Karl, Vogeser, Michael, Zachoval, Reinhart   +2 more
core   +1 more source