Results 101 to 110 of about 1,573,361 (315)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

[Laboratory diagnosis of HIV infection].

Le infezioni in medicina, 1996
The diagnosis of HIV infection is generally lead using two different ELISAs to detect specific anti-HIV antibodies, the eventual reactivity must then be confirmed by a Western Blot The antibodies can be detected only 1-6 months after the infection; in fact in the earliest phases neither the antibodies, for their low titre, nor the specific antigens ...
PANICO L, MARROCCO C, SCOLASTICO C, SAGNELLI E, FILIPPINI, Pietro   +4 more
openaire   +2 more sources

Laboratory diagnosis of viral infection

, 2014
Since the last Handbook of Clinical Neurology volume on this topic, viral diagnosis has made tremendous strides, moving from the margin to the mainstream of clinical care. For many years, conventional virus isolation was the mainstay of viral diagnosis since it was sensitive and “open-minded.” However, growth in conventional cell culture entails an ...
Peaper, David R., Landry, Marie Louise
openaire   +2 more sources

Sero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda. [PDF]

, 2010
BACKGROUND: Hepatitis B virus (HBV) infection is a global public health challenge. Prevalence of current hepatitis B virus infection in the general population in Uganda is about 10%.
Bwogi, Josephine, Abdhalah K Ziraba, Ziraba, Abdhalah K, Wainaina Caroline W, Mayanja-Kizza Harriet, Josephine Bwogi, Alice Namale, Namale Alice, Ziraba Abdhalah K, Harriet Mayanja-Kizza, Namale, Alice, Caroline W Wainaina, Bwogi Josephine, Mayanja-Kizza, Harriet, Wainaina, Caroline W   +14 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

In vitro laboratory infection research in orthopaedics: Why, when, and how. [PDF]

World J Orthop, 2023
Tsikopoulos K, Drago L, Meroni G, Kitridis D, Chalidis B, Papageorgiou F, Papaioannidou P.   +6 more
europepmc   +1 more source

Prevalence, risk factors and molecular epidemiology of highly resistant gram negative rods in hospitalized patients in the Dutch region Kennemerland

Antimicrobial Resistance and Infection Control, 2016
Background This paper describes (1) the Highly Resistant Gram Negative Rod (HR-GNR) prevalence rate, (2) their genotypes, acquired resistance genes and (3) associated risk factors of HR-GNR colonization among the hospitalized population in the Dutch ...
Dennis Souverein, Sjoerd M. Euser, Bjorn L. Herpers, Bram Diederen, Patricia Houtman, Marina van Seventer, Ingeborg van Ess, Jan Kluytmans, John W. A. Rossen, Jeroen W. Den Boer   +9 more
doaj   +1 more source

Evaluation of long-term pulmonary functions after COVID-19 infection in children: A longitudinal observational cohort study

Introduction: We aimed to present the changes that may occur in pulmonary functions in children who experienced more severe coronavirus disease 2019 (COVID-19) during long-term follow-up. Methodology: A prospective longitudinal observational cohort study
Korkmaz, Merve, Oral, Behiye, Senkan, Gülsüm E., Korkmaz, Muhammet F., Koç, İbrahim, Bozdemir, Sefika Elmas   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Effect of Virus-Specific Vaccination on Laboratory Infection Markers of Children with Acute Rotavirus-Associated Acute Gastroenteritis. [PDF]

Vaccines (Basel), 2023
Okuyan O, Elgormus Y, Sayili U, Dumur S, Isık OE, Uzun H.   +5 more
europepmc   +1 more source