Results 81 to 90 of about 173,668 (337)

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Labyrinth

, 2020
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
  +6 more sources

Intraspecific variation and symmetry of the inner-ear labyrinth in a population of wild turkeys: implications for paleontological reconstructions

PeerJ, 2019
The cochlea and semicircular canals (SCCs) of the inner ear are vital neurosensory devices. There are associations between the anatomy of these sensorineural structures, their function, and the function of related biological systems, for example, hearing
Donald G. Cerio, L. Witmer
semanticscholar   +1 more source

Analysis of dynamic characteristics of fluid force induced by labyrinth seal [PDF]

Flow patterns of the labyrinth seal are experimentally investigated for making a mathematical model of labyrinth seal and to obtain the flow induced force of the seal.
Iwatsubo, T., Kagawa, N., Kakiuchi, T., Kawai, R., Takahara, K.   +4 more
core   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

A Maze of the Living and the Dead: Mythologisation of the Space of Olšany Cemetery in the Trilogy “Trýznivé město” by Daniela Hodrová

Adeptus
This article is devoted to the issue of the mythologisation of the space of Olšany Cemetery performed by Daniela Hodrová in her trilogy Trýznivé město (City of Torment).
Zuzanna Woszczerowicz
doaj   +1 more source

Becoming the Labyrinth: Negotiating Magical Space and Identity in Puella Magi Madoka Magica

Humanities, 2016
In the magical girl anime series Puella Magi Madoka Magica, middle-school girls receive the power and responsibility to fight witches in exchange for making a wish.
Sara Cleto, Erin Kathleen Bahl
doaj   +1 more source

Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease

Investigative Ophthalmology and Visual Science, 2019
Purpose The basal surface of the retinal pigment epithelium (RPE) is folded into a complex basal labyrinth thought to facilitate solute and water transport.
M. Hayes, T. Burgoyne, Silène T. Wavre-Shapton, T. Tolmachova, M. Seabra, C. Futter   +5 more
semanticscholar   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Labyrinths

, 2023
A project about labyrinths. Project starts with looking at different kinds of reference labyinrhts to try to understand different kinds and different uses of labyrinths. Religious labyrinths, historical examples, labyrinths in movies and art. Then working with physical models of different kinds, investigating different spaces of different labyrinths ...
openaire   +3 more sources