Results 81 to 90 of about 152,483 (357)

The Labyrinth [PDF]

open access: yes, 2019
The Labyrinth is a puzzle video game meant to be experienced with a virtual reality headset. It aims to differ from typical puzzle games by being simultaneously fun, immersive, and mentally stimulating. The game consists of three unique level types, with
Nakamura, Derek   +2 more
core   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

“The Maze Factor” Vs. “The Solar Eye”: Identities of Walkers and Watchers [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2016
This paper will aim to investigate Joyce’s Ulysses, the paradigmatic urban novel, in juxtaposition with Huxley’s dystopian Brave New World and Alasdair Gray’s ambiguous Lanark on the theoretical basis of modern urban planning, environmental psychology,
Marija Spirkovska
doaj  

Dynamical Ordering of Driven Stripe Phases in Quenched Disorder

open access: yes, 2002
We examine the dynamics and stripe formation in a system with competing short and long range interactions in the presence of both an applied dc drive and quenched disorder. Without disorder, the system forms stripes organized in a labyrinth state.
A. R. Bishop   +11 more
core   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

On certain families of planar patterns and fractals

open access: yes, 2017
This survey article is dedicated to some families of fractals that were introduced and studied during the last decade, more precisely, families of Sierpi\'nski carpets: limit net sets, generalised Sierpi\'nski carpets and labyrinth fractals.
Cristea, Ligia L.
core   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

open access: yesAdvanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu   +10 more
wiley   +1 more source

La nueva imagen compleja del metamedio digital y su laberíntica interfaz

open access: yesCaracteres: Estudios Culturales y Críticos de la Esfera Digital, 2016
Through this article we move into the new status for the image, they have brought new digital technologies. In that sense, we analyse how its openness to continuous link puts as a complex maze without concrete support.
Ricardo González García
doaj  

Biophysical evaluation of the human vestibular system Semiannual status report, 1 Jul. - 31 Dec. 1966 [PDF]

open access: yes
Physical properties of labyrinth fluids in human vestibular ...
Meiry, J. L., Young, L. R.
core   +1 more source

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

open access: yesAdvanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang   +7 more
wiley   +1 more source

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