Results 71 to 80 of about 2,383,498 (219)

Thorncliffe Formation: A proglacial to subglacial lacustrine basin sequence, Greater Toronto Region, Canada

open access: yesBoreas, EarlyView.
Map of Lower sediment (LS) thickness is a surrogate for the distribution of Thorncliffe Formation (TF) and ~75% of TF thickness from the slope of Niagara Escarpment east to Brighton. Inset images show the LS sequence at the Don Valleys brickyards (DVBY) and undeformed TF sand and gravel (~15 m) below Newmarket Till (NT) at sites L and Co.
David R. Sharpe   +3 more
wiley   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

open access: yesBrain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle   +7 more
wiley   +1 more source

Metamaterials and Fluid Flows. [PDF]

open access: yesNat Commun
Avallone F   +22 more
europepmc   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro   +14 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Memantine prevents acute stress‐induced memory deficits by reversing sex‐dependent pathophysiological glutamatergic alterations in the dorsal hippocampus

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The neural mechanisms underlying effects of acute stress on memory are poorly understood. We demonstrated previously that acute stress produces identical spatial memory deficits in male and female mice but through distinct molecular mechanisms, with females exhibiting up‐regulation of N‐methyl‐D‐aspartate (NMDA) receptor
Sebastiano A. Torrisi   +13 more
wiley   +1 more source

Modern Perspectives on the Mechanisms and Non-Genetic Factors in Ménière's Disease-A Narrative Review. [PDF]

open access: yesBiomedicines
Iațentiuc IM   +12 more
europepmc   +1 more source

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