Results 101 to 110 of about 128,431 (240)

RNA polymerase structure and function at lac operon

open access: yesComptes Rendus. Biologies, 2005
Transcription of E. coli lac operon by RNA polymerase (RNAP) is a classic example of how the basic functions of this enzyme, specifically the ability to recognize/bind promoters, melt the DNA and initiate RNA synthesis, is positively regulated by transcription activators, such as cyclic AMP-receptor protein, CRP, and negatively regulated by lac ...
Sergei Borukhov, Jookyung Lee
openaire   +3 more sources

Engineered Living Energy Materials

open access: yesInterdisciplinary Materials, Volume 4, Issue 3, Page 412-455, May 2025.
Engineered living energy materials (ELEMs) are nascent research frontier for enabling sustainable energy conversion and storage. These materials exhibit unique characteristics such as self‐regeneration, biodegradability, environmental response, and evolutionary adaptability. This paper overviews different energy conversion bio‐modules, summarizes their
Xinyi Yuan   +14 more
wiley   +1 more source

Pre‐dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch

open access: yesMolecular Systems Biology, 2010
The lactose operon regulation in Escherichia coli is a primary model of phenotypic switching, reminiscent of cell fate determination in higher organisms.
Lydia Robert   +5 more
doaj   +1 more source

Identification of an intestine-specific promoter and inducible expression of bacterial α-galactosidase in mammalian cells by a lac operon system

open access: yesJournal of Animal Science and Biotechnology, 2012
Background α-galactosidase has been widely used in animal husbandry to reduce anti-nutritional factors (such as α-galactoside) in feed. Intestine-specific and substrate inducible expression of α-galactosidase would be highly beneficial for transgenic ...
Ya-Feng Zhai   +8 more
doaj   +1 more source

Subpopulations of sensorless bacteria drive fitness in fluctuating environments.

open access: yesPLoS Biology, 2020
Populations of bacteria often undergo a lag in growth when switching conditions. Because growth lags can be large compared to typical doubling times, variations in growth lag are an important but often overlooked component of bacterial fitness in ...
Thomas Julou   +4 more
doaj   +1 more source

Overlooked and misunderstood: A morpho‐molecular revision of Ditrichaceae s.str. (Dicranidae, Bryophyta), with a focus on the Holarctic species of Ditrichum

open access: yesTAXON, Volume 74, Issue 2, Page 223-259, April 2025.
Abstract We revised the Holarctic taxa of Ditrichaceae on the basis of both organellar DNA sequence data and morphological traits. After the removal of phylogenetically discordant elements related to Flexitrichum and Rhamphidium, the remaining representatives of the family cluster into three well‐supported lineages, which are recognized here as the ...
Vladimir Fedosov   +4 more
wiley   +1 more source

Stochastic approach to molecular interactions and computational theory of metabolic and genetic regulations

open access: yes, 2006
Binding and unbinding of ligands to specific sites of a macromolecule are one of the most elementary molecular interactions inside the cell that embody the computational processes of biological regulations.
Ackers   +35 more
core   +1 more source

A Single‐Plasmid Inducible‐Replication System for High‐Yield Production of Short Ff (f1, M13 or fd)‐Phage‐Derived Nanorods

open access: yesMicrobial Biotechnology, Volume 18, Issue 4, April 2025.
Single‐plasmid inducible‐replication system for biological nanorod production was developed based on the knowledge of replication and biology of the Ff (f1, fd or M13) bacteriophages from which they are derived. Design described here overcomes the replication bottlenecks, adjusts the production of the major coat protein and simplifies the preproduction
Rayén Ignacia León‐Quezada   +5 more
wiley   +1 more source

From adjacent activation in E. coli and DNA cyclization to eukaryotic enhancers : the elements of a puzzle.

open access: yesFrontiers in Genetics, 2014
DNA cyclization, E. coli lac repressor binding to two spaced lac operators and repression enhancement can be successfully used for a better understanding of the conditions required for interaction between eukaryotic enhancers and the machinery of ...
Michèle eAMOUYAL
doaj   +1 more source

Plasmid copy number underlies adaptive mutability in bacteria. [PDF]

open access: yes, 2014
The origin of mutations under selection has been intensively studied using the Cairns-Foster system, in which cells of an Escherichia coli lac mutant are plated on lactose and give rise to 100 Lac+ revertants over several days. These revertants have been
Aboubechara, John Paul   +4 more
core   +1 more source

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