Results 111 to 120 of about 113,489 (230)
Computer algebra in systems biology [PDF]
arXiv, 2007 Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for molecular biology and the development of advanced mathematical modeling techniques, this field promises to provide important new insights.
arxiv
Bistability of the lac operon during growth of Escherichia coli on lactose and lactose + glucose [PDF]
arXiv, 2007 The lac operon of Escherichia coli exhibits bistability. Early studies showed that bistability occurs during growth on TMG/succinate and lactose + glucose, but not during growth on lactose. More recent studies with lacGFP-transfected cells show bistability with TMG/succinate, but not with lactose and lactose + glucose.
arxiv
Visualization of the Dynamics of Gene Expression in the Living Mouse
Molecular Imaging, 2004 Reporter genes can monitor the status and activity of recombinant genomes in a diverse array of organisms, from bacteria and yeast to plants and animals.
Amy Ryan, Heidi Scrable
doaj +1 more source
Insights into the Geobacillus stearothermophilus species based on phylogenomic principles
BMC Microbiology, 2017 Background The genus Geobacillus comprises bacteria that are Gram positive, thermophilic spore-formers, which are found in a variety of environments from hot-springs, cool soils, to food manufacturing plants, including dairy manufacturing plants. Despite
S. A. Burgess +4 more
doaj +1 more source
Catabolite repression of the lac operon. Separate repression of two enzymes [PDF]
, 1969 Michael D. Yudkin
openalex +1 more source
DNA looping and physical constraints on transcription regulation [PDF]
J. Mol. Biol. 331, 981-989 (2003), 2004 DNA looping participates in transcriptional regulation, for instance, by allowing distal binding sites to act synergistically. Here we study this process and compare different regulatory mechanisms based on repression with and without looping. Within a simple mathematical model for the lac operon, we show that regulation based on DNA looping, in ...
arxiv
Paradoxical Effect of Weak Inducers on the lac Operon of Escherichia coli [PDF]
, 1968 Beverly Williams, Kenneth Paigen
openalex +1 more source
Mathematical Biosciences and Engineering, 2019 In this paper, we construct a discrete time delay Lac operon model with nonlinear degradation rate for mRNA, resulting from the interaction among several identical mRNA pieces.
Zenab Alrikaby +3 more
doaj +1 more source
Non-specific DNA Binding of Genome Regulating Proteins as a Biological Control Mechanism: 1. The lac Operon: Equilibrium Aspects [PDF]
, 1974 Peter H. von Hippel +3 more
openalex +1 more source
Characterization of Boolean Networks with Single or Bistable States [PDF]
arXiv, 2013 Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since understanding bistability is key for understanding these biological systems, mathematical modeling of the bistability ...
arxiv