Results 61 to 70 of about 36,597 (195)

Small Molecule‐Based Conditional Gene Regulation: Advances and Applications

open access: yesChemistry–Methods, Volume 6, Issue 4, April 2026.
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari   +3 more
wiley   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva   +3 more
wiley   +1 more source

The impact of metabolism on the adaptation of organisms to environmental change

open access: yesFrontiers in Cell and Developmental Biology, 2023
Since Jacob and Monod’s discovery of the lac operon ∼1960, the explanations offered for most metabolic adaptations have been genetic. The focus has been on the adaptive changes in gene expression that occur, which are often referred to as “metabolic ...
Douglas L. Rothman   +6 more
doaj   +1 more source

Rhizobial motility preference in root colonization of Medicago truncatula

open access: yesNew Phytologist, Volume 250, Issue 1, Page 547-562, April 2026.
Summary Tunnel‐like infection thread (IT) structures support root colonization by symbiotic nitrogen‐fixing rhizobia bacteria in most legume species. These tip‐grown structures are key to directing rhizobia from root hairs to developing nodules, where they are hosted to fix nitrogen.
Anaïs Delers   +11 more
wiley   +1 more source

EtcABC, a Putative EII Complex, Regulates Type 3 Fimbriae via CRP-cAMP Signaling in Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2019
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan   +5 more
doaj   +1 more source

Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824. [PDF]

open access: yes, 2013
Background: Consolidated bioprocessing (CBP) is reliant on the simultaneous enzyme production, saccharification of biomass, and fermentation of released sugars into valuable products such as butanol. Clostridial species that produce butanol are, however,
Bolam, DN   +7 more
core   +1 more source

The lac operon galactoside acetyltransferase

open access: yesComptes Rendus. Biologies, 2005
Of the proteins encoded by the three structural genes of the lac operon, the galactoside acetyltransferase (thiogalactoside transacetylase, LacA, GAT) encoded by lacA is the only protein whose biological role remains in doubt.
openaire   +2 more sources

The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus. [PDF]

open access: yesPLoS ONE, 2012
Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level, and the Pspac-driven opuCABCD partially complements the lethal effects of yhcS antisense RNA ...
Meiying Yan   +3 more
doaj   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu   +8 more
wiley   +1 more source

Analysis of the lactose metabolism in E. coli using sum-of-squares decomposition [PDF]

open access: yes, 2005
We provide a system-theoretic analysis of the mathematical model of lactose induction in E.coli which predicts the level of lactose induction into the cell for specified values of external lactose.
Ahmadzadeh, Ali   +4 more
core  

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