Results 51 to 60 of about 21,116 (197)
Comparison of deterministic and stochastic models of the lac operon genetic network. [PDF]
The lac operon has been a paradigm for genetic regulation with positive feedback, and several modeling studies have described its dynamics at various levels of detail.
Stamatakis M, Mantzaris NV.
europepmc +2 more sources
The lac operon is one of the best known gene regulatory circuits and constitutes a landmark example of how bacteria tune their metabolism to nutritional conditions.
Ana Sousa (261625) +3 more
core +1 more source
Stochastic stability and observer design for the lac operon model
The aim of this study is to investigate the stability properties of a model of the lac operon enhanced with stochastic perturbations. New sufficient conditions of exponential mean square stability are obtained analytically for this model and threshold ...
AA Ben Halim (15800534) +2 more
core +2 more sources
The impact of metabolism on the adaptation of organisms to environmental change
Since Jacob and Monod’s discovery of the lac operon ∼1960, the explanations offered for most metabolic adaptations have been genetic. The focus has been on the adaptive changes in gene expression that occur, which are often referred to as “metabolic ...
Douglas L. Rothman +6 more
doaj +1 more source
The lac operon is one of the best known gene regulatory circuits and constitutes a landmark example of how bacteria tune their metabolism to nutritional conditions.
Ana Sousa (261625) +3 more
core +1 more source
Abstract Zinc finger proteins are essential for the proper functioning of eukaryotic organisms, while their artificial variants can be used in cancer therapy or gene editing via their specific DNA recognition. Zn(II) binding is indispensable for the structural integrity of zinc fingers.
Bálint Hajdu +8 more
wiley +1 more source
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan +5 more
doaj +1 more source
The lac operon galactoside acetyltransferase
Of the proteins encoded by the three structural genes of the lac operon, the galactoside acetyltransferase (thiogalactoside transacetylase, LacA, GAT) encoded by lacA is the only protein whose biological role remains in doubt.
openaire +2 more sources
The lac operon is one of the best known gene regulatory circuits and constitutes a landmark example of how bacteria tune their metabolism to nutritional conditions.
Ana Sousa (261625) +3 more
core +1 more source
Pseudomonas putida KT2440 grows on polyethylene‐derived long‐chain alcohols (C16OH, C20OH) as sole carbon sources. Adaptive laboratory evolution rapidly increases growth, converging on envelope‐associated mutations. Expressing the outer‐membrane transporter AlkL recapitulates much of the evolved phenotype, identifying substrate access and membrane ...
Raul Mireles, Lianet Noda‐García
wiley +1 more source

