Results 31 to 40 of about 21,116 (197)
Divergent Evolution and Local Establishment of Multidrug-Resistant <i>Shigella sonnei</i> in China. [PDF]
MedComm (2020)• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Liu K +26 more
europepmc +2 more sources
CadC-mediated activation of the cadBA promoter in Escherichia coli [PDF]
, 2005 The transcriptional activator CadC in Escherichia coli, a member of the ToxR-like proteins, activates transcription of the cadBA operon encoding the lysine decarboxylase CadA and the lysine-cadaverine antiporter CadB. cadBA is induced under conditions of
Kuper, C., Jung, K.
core +1 more source
Physiological regulation of a decontrolled lac operon [PDF]
Journal of Bacteriology, 1977 The expression of the lac operon was studied under a variety of growth conditions in induced and in constitutive cells of Escherichia coli that carried different catabolite-insensitive lac promoters. Use of such "decontrolled" lac operons permitted a study of the expression of an operon that was presumably subject only to passive control. Since the use
B L, Wanner, R, Kodaira, F C, Neidhardt
openaire +2 more sources
Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics
Molecular Therapy: Nucleic Acids, 2013 Development of RNAi-based therapeutics has the potential to revolutionize treatment options for a range of human diseases. However, as with gene therapy, a major barrier to progress is the lack of methods to achieve and measure efficient delivery for ...
Mark Stevenson +9 more
doaj +1 more source
MicrobiologyOpen, 2019 Bacteria can utilize diverse sugars as carbon and energy source, but the regulatory mechanisms directing the choice of the preferred substrate are often poorly understood.
Tamara Aleksandrzak‐Piekarczyk +2 more
doaj +1 more source
A modified consumer inkjet for spatiotemporal control of gene expression.
PLoS ONE, 2009 This paper presents a low-cost inkjet dosing system capable of continuous, two-dimensional spatiotemporal regulation of gene expression via delivery of diffusible regulators to a custom-mounted gel culture of E. coli. A consumer-grade, inkjet printer was
Daniel J Cohen +2 more
doaj +1 more source
Biomedical and Biotechnology Research Journal, 2022 Background: The repeating elements in the genes or genomes of living organisms are associated with a variety of functions at the molecular level. Mirror repeats (MRs) are unique type of repeat sequences among them, which are found to be linked with H-DNA
Sandeep Yadav +2 more
doaj +1 more source
Microbial Cell Factories, 2012 Background The E. coli lac operon and its components have been studied for decades, and lac-derived systems are widely used for recombinant protein production.
Fernández-Castané Alfred +2 more
doaj +1 more source
Use of a Role-Playing Activity To Increase Student Understanding of Bacterial Gene Regulation
Journal of Microbiology & Biology Education, 2023 Undergraduate students often struggle to understand the basics of bacterial gene regulation, a key concept in microbiology. They find it hard to visualize the architecture of a bacterial operon or how the gene, RNA, and protein components interact with ...
Vinaya Sampath
doaj +1 more source
From Binary to Multivalued to Continuous Models: The lac Operon as a Case Study
Journal of Integrative Bioinformatics, 2010 Using the lac operon as a paradigmatic example for a gene regulatory system in prokaryotes, we demonstrate how qualitative knowledge can be initially captured using simple discrete (Boolean) models and then stepwise refined to multivalued logical models ...
Franke Raimo +2 more
doaj +2 more sources